Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
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Ubc13: the Lys63 ubiquitin chain building machineHypoxia Induced NF-κBCrosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during InflammationEmerging co-morbidities of obstructive sleep apnea: cognition, kidney disease, and cancerSubstrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling PathwaysFIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1REST is a hypoxia-responsive transcriptional repressorThe prolyl hydroxylase inhibitor dimethyloxalylglycine enhances dentin sialophoshoprotein expression through VEGF-induced Runx2 stabilizationTargeting hypoxia signalling for the treatment of ischaemic and inflammatory diseasesIdentification of prolyl hydroxylation modifications in mammalian cell proteins.Bone marrow derived mesenchymal stem cells alleviated brain injury via down-regulation of interleukin-1β in focal cerebral ischemic ratsAnkyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response PathwayHypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκBInterleukin-1β Affects MDAMB231 Breast Cancer Cell Migration under Hypoxia: Role of HIF-1α and NFκB Transcription Factors.Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses.Hypoxia and inflammation are two sides of the same coinImmunologic Consequences of Hypoxia during Critical Illness.Hypoxia-sensitive pathways in inflammation-driven fibrosis.Iron and oxygen sensing: a tale of 2 interacting elements?Inflammatory response mechanisms exacerbating hypoxemia in coexistent pulmonary fibrosis and sleep apnea.Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications.HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond.Understanding complexity in the HIF signaling pathway using systems biology and mathematical modeling.Inhibition of Prolyl Hydroxylase Attenuates Fas Ligand-Induced Apoptosis and Lung Injury in Mice.PHD1 regulates p53-mediated colorectal cancer chemoresistance.Hypoxia-dependent regulation of inflammatory pathways in immune cellsRespiratory gases and the regulation of transcription.New Insights into Protein Hydroxylation and Its Important Role in Human Diseases.Therapeutic inhibition of prolyl hydroxylase domain-containing enzymes in surgery: putative applications and challenges.Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function.REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia.Activation of HIF-1α does not increase intestinal tumorigenesis.Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions.Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD.Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPAR γ in radiation-induced fibrosis.Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways.Interactions Between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma on Neuroinflammation, Demyelination, and Remyelination in Multiple Sclerosis.Hypoxia-Inducible Factor and Its Role in the Management of Anemia in Chronic Kidney Disease.Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
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Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of IL-1β-induced NF ...... flammatory signaling pathways.
@en
Regulation of IL-1β-induced NF ...... flammatory signaling pathways.
@nl
type
label
Regulation of IL-1β-induced NF ...... flammatory signaling pathways.
@en
Regulation of IL-1β-induced NF ...... flammatory signaling pathways.
@nl
prefLabel
Regulation of IL-1β-induced NF ...... flammatory signaling pathways.
@en
Regulation of IL-1β-induced NF ...... flammatory signaling pathways.
@nl
P2860
P50
P921
P356
P1476
Regulation of IL-1β-induced NF ...... nflammatory signaling pathways
@en
P2093
Philip Cotter
Ulrike Bruning
P2860
P304
18490-18495
P356
10.1073/PNAS.1309718110
P407
P50
P577
2013-10-21T00:00:00Z