GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy.
about
Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphaneExtracellular cGMP Modulates Learning Biphasically by Modulating Glycine Receptors, CaMKII and Glutamate-Nitric Oxide-cGMP Pathway.Hyperammonemia alters glycinergic neurotransmission and modulation of the glutamate-nitric oxide-cGMP pathway by extracellular glycine in cerebellum in vivo.Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy.Recent advances in hepatic encephalopathy.Lactulose decreases neuronal activation and attenuates motor behavioral deficits in hyperammonemic rats.GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study.Update on the Therapeutic Management of Hepatic Encephalopathy.
P2860
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P2860
GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@en
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@nl
type
label
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@en
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@nl
prefLabel
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@en
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@nl
P2093
P2860
P356
P1476
GR3027 antagonizes GABAA recep ...... ia and hepatic encephalopathy.
@en
P2093
Ana Agusti
Carmina Montoliu
Evgenya Malinina
Gianna Ragagnin
Jessica Strömberg
Magnus Doverskog
Maja Johansson
Marta Llansola
P2860
P304
P356
10.1152/AJPGI.00073.2015
P577
2015-07-02T00:00:00Z