Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells. - Wikidata - awgldk - TriplyDB

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

http://www.wikidata.org/entity/Q37322185

about

IL-21 Signaling in Immunity Stable long-term cultures of self-renewing B cells and their applications ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.Advances of the interleukin-21 signaling pathway in immunity and angiogenesis.Human CD38hiCD138⁺ plasma cells can be generated in vitro from CD40-activated switched-memory B lymphocytes STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function Rapid Proliferation and Differentiation of a Subset of Circulating IgM Memory B Cells to a CpG/Cytokine Stimulus In Vitro The Ying and Yang of STAT3 in Human Disease Signal transducer and activator of transcription 3: a year in review.STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus.Ablation of STAT3 in the B Cell Compartment Restricts Gammaherpesvirus Latency In Vivo.Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets.MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis.Tyrosine kinase c-Abl regulates the survival of plasma cells Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage.Cellular and chromatin dynamics of antibody-secreting plasma cells.EBV epigenetically suppresses the B cell-to-plasma cell differentiation pathway while establishing long-term latency.Porcine Reproductive and Respiratory Syndrome Virus Antagonizes JAK/STAT3 Signaling via nsp5, Which Induces STAT3 Degradation.Efficient Culture of Human Naive and Memory B Cells for Use as APCs.The Role of STAT Signaling Pathways in the Pathogenesis of Systemic Lupus Erythematosus.IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement.Successful haploidentical donor hematopoietic stem cell transplant and restoration of STAT3 function in an adolescent with autosomal dominant hyper-IgE syndrome.Perturbation of B Cell Gene Expression Persists in HIV-Infected Children Despite Effective Antiretroviral Therapy and Predicts H1N1 Response.Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity Combined immunodeficiency with CD4 lymphopenia and sclerosing cholangitis caused by a novel loss-of-function mutation affecting IL21R.Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency.Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains.Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.IL10 receptor is a novel therapeutic target in DLBCLs.Psoriasis: A STAT3-Centric View.Modulation of the Interleukin-21 Pathway with Interleukin-4 Distinguishes Common Variable Immunodeficiency Patients with More Non-infectious Clinical Complications.Evaluation of the role of stat3 in antibody and TH17-mediated responses to pneumococcal immunization and infection using a mouse model of Autosomal Dominant Hyper IgE Syndrome.Condition-dependent generation of aquaporin-4 antibodies from circulating B cells in neuromyelitis optica.Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses.Somatic mosaicism in B cells of a patient with autosomal dominant hyper IgE syndrome.Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective.

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P2860

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

http://www.wikidata.org/entity/Q37322185

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

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2013年學術文章

@zh-hant

name

Naive and memory human B cells ...... tibody-secreting plasma cells.

@en

Naive and memory human B cells ...... tibody-secreting plasma cells.

@nl

type

label

Naive and memory human B cells ...... tibody-secreting plasma cells.

@en

Naive and memory human B cells ...... tibody-secreting plasma cells.

@nl

prefLabel

Naive and memory human B cells ...... tibody-secreting plasma cells.

@en

Naive and memory human B cells ...... tibody-secreting plasma cells.

@nl

P1433

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P1433

Journal of Experimental Medicine

P1476

Naive and memory human B cells ...... ntibody-secreting plasma cells

@en

P2093

Anna Chan

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Christoph Klein

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Dan Engelhard

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Danielle T Avery

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David A Fulcher

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Diana Averbuch

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Jane Peake

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Jennifer L Stoddard

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Joachim Roesler

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Joanne M Smart

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P2860

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-

B cell differentiation and isotype switching is related to division cycle number

Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes

Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

STAT3 mutations in the hyper-IgE syndrome

Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells

Intrinsic differences in the initiation of B cell receptor signaling favor responses of human IgG(+) memory B cells over IgM(+) naive B cells.

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2739-2753

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10.1084/JEM.20130323

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12

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210

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Jean-Laurent Casanova

Capucine Picard

Elissa K. Deenick

Peter D Arkwright

Stephanie Boisson-Dupuis

Jacinta Bustamante

Martyn A. French

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2013-11-11T00:00:00Z

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24218138

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