Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.

Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.

Item
http://www.wikidata.org/entity/Q37325608
Safety, efficacy and efficiency of laser-assisted IVF in subfertile mutant mouse strainsProhormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice.A Challenging Form of Non-autoimmune Insulin-Dependent Diabetes in a Wolfram Syndrome Patient with a Novel Sequence Variant.Identification of homozygous WFS1 mutations (p.Asp211Asn, p.Gln486*) causing severe Wolfram syndrome and first report of male fertility.Endocrine and metabolic aspects of the Wolfram syndrome.Hypothalamic gene expression profile indicates a reduction in G protein signaling in the Wfs1 mutant mice.Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.CRISPR/Cas9-mediated targeting of the Rosa26 locus produces Cre reporter rat strains for monitoring Cre/loxP-mediated lineage tracing.
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Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.

Item
http://www.wikidata.org/entity/Q37325608
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.
@en
Male mice with deleted Wolframin
@nl
type
label
Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.
@en
Male mice with deleted Wolframin
@nl
prefLabel
Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.
@en
Male mice with deleted Wolframin
@nl
P1433
P1476
P2093
P2860
P2888
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P356
P478
P50
P577
P5875
P6179
P698
P932
P356
P1433
P1476
Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.
@en
P2093
P2860
P2888
P304
P31
P356
P478
P50
P577
P5875
P6179
P698
P932