Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. - Wikidata - awgldk - TriplyDB

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

http://www.wikidata.org/entity/Q37330584

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PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression Cellular and Molecular Mechanisms of Chronic Kidney Disease with Diabetes Mellitus and Cardiovascular Diseases as Its Comorbidities A tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiation TGF-β/Smad signaling in renal fibrosis Key Fibrogenic Signaling Targeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver Fibrosis A proteomics approach to identifying key protein targets involved in VEGF inhibitor mediated attenuation of bleomycin-induced pulmonary fibrosis tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling Single-nucleotide polymorphisms of the dopamine D2 receptor increase inflammation and fibrosis in human renal proximal tubule cells.Increasing cGMP-dependent protein kinase activity attenuates unilateral ureteral obstruction-induced renal fibrosis.Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling.ß-Catenin is markedly induced in a murine model of an arteriovenous fistula: the effect of metalloproteinase inhibition Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury.Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis.AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration.Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria.Multiple genes of the renin-angiotensin system are novel targets of Wnt/β-catenin signaling.Canonical Wnt/β-catenin signaling mediates transforming growth factor-β1-driven podocyte injury and proteinuria.Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance.Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis.Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.aV integrins and TGF-β-induced EMT: a circle of regulation Tubular cell dedifferentiation and peritubular inflammation are coupled by the transcription regulator Id1 in renal fibrogenesis.Cellular and molecular mechanisms of renal fibrosis.Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis.New insights into epithelial-mesenchymal transition in kidney fibrosis.Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis.Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model Renal integrin-linked kinase depletion induces kidney cGMP axis upregulation: Consequences on basal and acutely damaged renal function TGF-β signaling in the kidney: profibrotic and protective effects Epithelial-mesenchymal transition in renal fibrosis - evidence for and against.Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects.Pathophysiology of the diabetic kidney.Integrins and integrin-related proteins in cardiac fibrosis.TGF-β: the connecting link between nephropathy and fibrosis.Ferulic Acid Attenuates TGF-β1-Induced Renal Cellular Fibrosis in NRK-52E Cells by Inhibiting Smad/ILK/Snail Pathway.Snail and kidney fibrosis.Integrin-linked kinase: a new member of the kinases involved in hypertensive end-organ damage?

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P2860

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

http://www.wikidata.org/entity/Q37330584

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 18 June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@en

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@nl

type

label

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@en

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@nl

prefLabel

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@en

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@nl

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Journal of the American Society of Nephrology

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Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.

@en

P2093

Chunsun Dai

http://www.w3.org/2001/XMLSchema#string

Dan Wang

http://www.w3.org/2001/XMLSchema#string

Donna B Stolz

http://www.w3.org/2001/XMLSchema#string

Xiaoyue Tan

http://www.w3.org/2001/XMLSchema#string

Yingjian Li

http://www.w3.org/2001/XMLSchema#string

Youhua Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Epithelial-mesenchymal transition and its implications for fibrosis

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

The distribution and regulation of integrin-linked kinase in normal and diabetic kidneys

Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

Evidence that fibroblasts derive from epithelium during tissue fibrosis

Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase.

The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

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1907-1918

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scholarly article

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10.1681/ASN.2008090930

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9

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20

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2009-06-18T00:00:00Z

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19541809

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2736781

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