Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours.
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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studiesEpigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumorsMAPK pathway activation in pilocytic astrocytomaThe molecular biology of WHO grade I astrocytomasWill kinase inhibitors make it as glioblastoma drugs?Pathological and molecular advances in pediatric low-grade astrocytomaPilocytic astrocytoma: a disease with evolving molecular heterogeneityMolecular Markers in Low-Grade Glioma-Toward Tumor ReclassificationA new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.Pediatric low-grade gliomas: how modern biology reshapes the clinical field.BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.Identification of transcriptional regulatory networks specific to pilocytic astrocytoma.Differences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.Extracellular vesicles as prospective carriers of oncogenic protein signatures in adult and paediatric brain tumours.An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in miceChromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas.Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.A pilot study using carboplatin, vincristine, and temozolomide in children with progressive/symptomatic low-grade glioma: a Children's Oncology Group study†Novel BRAF Alteration in a Sporadic Pilocytic Astrocytoma.BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the CerebellumPI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma.BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper.BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.Molecular markers in pediatric neuro-oncology.Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner.MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2.Analysis of the BRAF(V600E) Mutation in Central Nervous System Tumors.Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age.Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas.Conditional KIAA1549:BRAF mice reveal brain region- and cell type-specific effects.Challenges in Drug Discovery for Neurofibromatosis Type 1-Associated Low-Grade GliomaTargeting Ras-RAF-ERK and its interactive pathways as a novel therapy for malignant gliomas.Review: low-grade gliomas as neurodevelopmental disorders: insights from mouse models of neurofibromatosis-1.Long-term epilepsy-associated tumors.Molecular markers of glioma: an update on recent progress and perspectives.Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.The molecular and cell biology of pediatric low-grade gliomas.Pediatric high-grade astrocytomas: a distinct neuro-oncological paradigm.Targeted therapy in pediatric low-grade glioma.
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Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@en
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@nl
type
label
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@en
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@nl
prefLabel
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@en
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@nl
P2093
P2860
P356
P1476
Duplication of 7q34 is specifi ...... lar and optic pathway tumours.
@en
P2093
A Montpetit
J Atkinson
J L Montes
J-P Farmer
P2860
P2888
P304
P356
10.1038/SJ.BJC.6605179
P407
P577
2009-07-14T00:00:00Z