Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail. - Wikidata - awgldk - TriplyDB

Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.

Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.

http://www.wikidata.org/entity/Q38083799

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An integrative view on sex differences in brain tumors Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Single vs. combination immunotherapeutic strategies for glioma.Actionable molecular biomarkers in primary brain tumors.Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas.Remaining challenges in childhood cancer and newer targeted therapeutics.Management of high-grade gliomas in the pediatric patient: Past, present, and future.Biomarker-based prognostic stratification of young adult glioblastoma Primary Glial and Neuronal Tumors of the Ovary or Peritoneum: A Clinicopathologic Study of 11 Cases.Is glioblastoma an epigenetic malignancy?Recent advances and future of immunotherapy for glioblastoma.H3F3A K27M mutations in thalamic gliomas from young adult patients.Reshaping chromatin after DNA damage: the choreography of histone proteins.Unreported intrinsic disorder in proteins: Disorder emergency room.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.Pediatric high-grade astrocytomas: a distinct neuro-oncological paradigm.Epigenetics components of aging in the central nervous system.Histone H3.3 mutations: a variant path to cancer.Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment.Identification of recurrent SMO and BRAF mutations in ameloblastomas Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma.Imaging Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3 K27M Mutation.Assessment of programmed death-ligand 1 expression and tumor-associated immune cells in pediatric cancer tissues.H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.Molecular alterations in pediatric brainstem gliomas.Molecular Basis of Pediatric Brain Tumors.Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location.Altered global histone-trimethylation code and H3F3A-ATRX mutation in pediatric GBM.

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Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.

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Brain Pathology

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Chromatin remodeling defects i ...... e of a variant histone 3 tail.

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Adam M Fontebasso

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Dominik Sturm

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Xiao-Yang Liu

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P2860

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

Dissecting the genomic complexity underlying medulloblastoma

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

An integrated genomic analysis of human glioblastoma multiforme

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210-216

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scholarly article

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10.1111/BPA.12023

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2

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23

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2013-03-01T00:00:00Z

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