Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes. - Wikidata - awgldk - TriplyDB

Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes.

Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes.

http://www.wikidata.org/entity/Q37331302

about

Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals Roles for CCN2 in normal physiological processes Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets Hepatotoxicity or hepatoprotection? Pattern recognition for the paradoxical effect of the Chinese herb Rheum palmatum L. in treating rat liver injury Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation.TGF-β-independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC Enhanced Wnt Signalling in Hepatocytes is Associated with Schistosoma japonicum Infection and Contributes to Liver Fibrosis.A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high.Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein A quantitative study of the mechanisms behind thymic atrophy in Gαi2-deficient mice during colitis development Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes.Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis.Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.Connective tissue growth factor and cardiac diastolic dysfunction: human data from the Taiwan diastolic heart failure registry and molecular basis by cellular and animal models.Role of CTGF gene promoter methylation in the development of hepatic fibrosis Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.A virus-like particle-based connective tissue growth factor vaccine suppresses carbon tetrachloride-induced hepatic fibrosis in mice Members of the Cyr61/CTGF/NOV Protein Family: Emerging Players in Hepatic Progenitor Cell Activation and Intrahepatic Cholangiocarcinoma.Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis.Translating an understanding of the pathogenesis of hepatic fibrosis to novel therapies Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissues Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2).Serine protease inhibitor Kazal type 1 promotes epithelial-mesenchymal transition through EGFR signaling pathway in prostate cancer.CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC.Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice.Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes.Ethanol-stimulated differentiated functions of human or mouse hepatic stellate cells are mediated by connective tissue growth factor.Hepatocyte-derived Snail1 propagates liver fibrosis progression.TGF-β signaling regulates fibrotic expression and activity in carpal tunnel syndrome.Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation.Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2).Connective tissue growth factor production by activated pancreatic stellate cells in mouse alcoholic chronic pancreatitis.Connective Tissue Growth Factor Transgenic Mouse Develops Cardiac Hypertrophy, Lean Body Mass and Alopecia.Connective Tissue Growth Factor Transgenic Mouse Develops Cardiac Hypertrophy, Lean Body Mass and Alopecia.Regulation and bioactivity of the CCN family of genes and proteins in obesity and diabetes.Analysis of Pathological Activities of CCN Proteins in Fibrotic Diseases: Kidney Fibrosis.Effects of Ganfukang on expression of connective tissue growth factor and focal adhesion kinase/protein kinase B signal pathway in hepatic fibrosis rats.

P2860

Q24648246-CC81A58E-A863-40DB-8DC7-FE5E2614E65C Q28246114-27B67742-1456-487D-A29E-19CFC467C832 Q28254386-0AE82D7F-40E1-4822-A35E-2AF9DB42C67F Q28476818-03DA8684-9A75-4BC0-8AA1-AE1F0BC9F70C Q33390722-CDAD7A14-DA68-4400-B622-5AC1976D60C5 Q33591632-2ECF91B3-9ABF-4701-9830-DAF3F252F96D Q33671258-C35BC928-D16C-4DBC-BF5B-954C6C15E212 Q33705086-028712EB-4750-4FE7-8290-FDDBC61FC909 Q33786810-C6BF6638-7491-4B49-8248-FDC5EE9DB59A Q34270961-3D33E27B-9A9F-4B33-8A13-D41BC439BA7F Q34441588-64AFC4F4-D5BC-47BE-8B0A-C1DC8949451E Q34721223-BA42C489-D872-4861-BCA2-AE478C395560 Q35002110-B3B958AF-1AC4-46D4-A7F3-980DDDF43EF0 Q35086172-BF85E5FE-EDA9-4E66-B7AF-37AAB551C877 Q36595114-5B819D95-1C82-4C89-B113-66B59C232028 Q36812375-ADD75E1A-D2A8-4042-86BA-4020DC7A09F9 Q37209120-3413B301-B1CB-4D5C-9801-5F715512A023 Q37382474-804AA9EA-DA12-4A17-A601-012380331CB8 Q37684726-0CD78027-2B36-46FD-B5EA-4378F6947748 Q38073028-FF42D701-81F0-4948-B4A7-DB68F4B50DFD Q38097283-EE21009F-774E-40C2-AD8B-AA24FCE21A05 Q39002130-98E67325-D87D-4E69-BF08-4DE3036D4B77 Q39016331-62547247-636D-4085-AC7F-5A1CC2C06095 Q39508427-362A9460-394F-47F6-8B7E-3F80CEE2D1FD Q39508688-F77321FC-EB64-4FC1-8730-09208E846670 Q39558073-943EE8C1-AFD8-455F-906E-82C1A155F8FF Q39620314-D73AFB89-7810-499F-917B-05E41892B2AE Q41865587-0A3A0607-1BBB-4047-9628-348B3DAECC62 Q41956286-26C37E01-6F2B-4D99-A476-936F23EF0A72 Q42492308-5FD69628-B948-4229-A756-663817AFC8F6 Q42632299-7B96FC3E-30A4-40BB-83CC-73B9D111EE75 Q42735371-CFD2CC48-8ED7-4BA7-942A-D2429C756B3B Q45806957-82E1E691-8758-4412-A33D-C1C11CE7E485 Q47688654-3F617EC3-81AD-49A1-83A7-580D75F53C4F Q50145564-C6709B13-E296-4AE4-B96F-F5C087E02C5F Q51400215-A4A0D8E7-342D-44A4-A7DC-903B8DF75CDA Q54412159-9509EC73-9A43-4FD9-8A16-6743CA84C692

P2860

Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes.

http://www.wikidata.org/entity/Q37331302

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on September 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@en

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@nl

type

label

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@en

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@nl

prefLabel

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@en

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@nl

P1433

Q37331302-29FA6A0C-70EE-40C0-A586-72C86475552F

P1476

Q37331302-85876B9D-9CBF-4C36-A491-731214EEC10D

P2093

Q37331302-4E4617AF-4265-4E79-B742-CB375CAB1DA2

Q37331302-5FAE9F1A-42F3-4BDD-B99E-8B91BEAF253F

Q37331302-7AE24F87-6076-434C-B0E6-16BB973B9AD7

Q37331302-8E431BA4-AD32-47F6-9771-4F14EBCF8DBF

Q37331302-AA216570-679B-41A0-9A4F-5F757980C828

Q37331302-E1420D7B-D86D-4328-AD72-4CC9BCCF92E6

P2860

Q37331302-006A65CE-CFEB-46AD-91F1-F7AFC83B9BF3

Q37331302-0A07AC1A-8772-4236-B614-562A0B4B77FB

Q37331302-0D7E1D9D-7C57-4FA0-BC21-FB7690941C7F

Q37331302-3556CE8B-77C4-43F7-B364-B8D903FA9B38

Q37331302-369CDF2F-BE84-423B-9D6A-DDC7680D87C6

Q37331302-47F134B3-58E4-4E59-A7EC-CBD00BC7360A

Q37331302-4D02C140-5D64-4F02-A7DB-6374E90C284C

Q37331302-4FC1F01F-DACB-4B1D-BF93-A699D7B6FC5D

Q37331302-5543C7E5-68D9-4CE8-8E91-40AA9FD85083

Q37331302-5B8F5C53-40BC-44B4-A03C-352CE00E8A36

P304

Q37331302-5954539D-4ABE-49B4-A2A1-8D8628781D5F

P31

Q37331302-B9A115FB-11AC-44BA-BBCD-F49E4B83FC38

P356

Q37331302-EFE5E3E1-9C39-46A7-A717-4E750B9F0EF2

P407

Q37331302-9C01CFB8-7C96-4C7B-8070-AAFB0B8E6DFF

P433

Q37331302-EF7292EB-67E3-4E2F-A318-9AECE2797EB2

P478

Q37331302-189432CE-FEEE-44F0-9729-6BDFFABE7FE9

P577

Q37331302-B9ED3D7C-036C-4F85-914D-9CAFCCEE4A5B

P5875

Q37331302-12D2C02E-64E7-404D-94F0-A69986EDD536

P698

Q37331302-AF90FF47-4C3F-4962-8FC0-8412EB66C258

P921

Q37331302-10AC22E1-BFA4-4BA6-8D96-2541165D336D

P932

Q37331302-63906874-93C0-4C59-969A-5D9CA306A7BE

P356

P1433

P1476

Susceptibility to liver fibros ...... ctor transgene in hepatocytes.

@en

P2093

Bernard Perbal

http://www.w3.org/2001/XMLSchema#string

Daniel S Alt

http://www.w3.org/2001/XMLSchema#string

David R Brigstock

http://www.w3.org/2001/XMLSchema#string

Ruju Chen

http://www.w3.org/2001/XMLSchema#string

Sherri Kemper

http://www.w3.org/2001/XMLSchema#string

Zhenyue Tong

http://www.w3.org/2001/XMLSchema#string

P2860

CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1

Functions and mechanisms of action of CCN matricellular proteins

Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model

Physical mapping of human loci homologous to the chicken nov proto-oncogene

Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes

Steroidal regulation of connective tissue growth factor (CCN2; CTGF) synthesis in the mouse uterus.

Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis

Overexpression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism

Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation

P304

939-947

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/HEP.23102

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

50

http://www.w3.org/2001/XMLSchema#string

P577

2009-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26731980

http://www.w3.org/2001/XMLSchema#string

P698

19670427

http://www.w3.org/2001/XMLSchema#string

P921

connective tissue

P932

2737071

http://www.w3.org/2001/XMLSchema#string