The double-edged sword of autophagy modulation in cancer.
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Combined RNAi-mediated suppression of Rictor and EGFR resulted in complete tumor regression in an orthotopic glioblastoma tumor modelAutolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalkUV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activationAstrocyte elevated gene-1 induces protective autophagyLysosomal transmembrane protein LAPTM4B promotes autophagy and tolerance to metabolic stress in cancer cellsLithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cellsTargeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapyBlue-Print Autophagy: Potential for Cancer TreatmentAutophagy, cell death, and cancerAutophagy: a new target for nonalcoholic fatty liver disease therapyAutophagy-Related Deubiquitinating Enzymes Involved in Health and DiseaseAMPK as a potential anticancer target - friend or foe?Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implicationsAutophagy and cancerStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewAutophagy and endocrine resistance in breast cancerAutophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibitionPhotodynamic N-TiO2 Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia CellsGlioblastoma, hypoxia and autophagy: a survival-prone 'ménage-à-trois'Macrophage migration inhibitory factor: a potential driver and biomarker for head and neck squamous cell carcinomaRoles of autophagy induced by natural compounds in prostate cancerNedd4 E3 ubiquitin ligase promotes cell proliferation and autophagyProtectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and CancerAutophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicityRETRACTED: Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced CarcinogenesisSustained proliferation in cancer: Mechanisms and novel therapeutic targetsAutophagy inhibition enhances daunorubicin-induced apoptosis in K562 cellsThymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cellsUlinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagyApoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer CellsTetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01Autophagy and metabolismPancreatic cancers require autophagy for tumor growthAutophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy.ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagyEGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complexCowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells.Chloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cellsCurcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNASpecific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.
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The double-edged sword of autophagy modulation in cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The double-edged sword of autophagy modulation in cancer.
@en
The double-edged sword of autophagy modulation in cancer.
@nl
type
label
The double-edged sword of autophagy modulation in cancer.
@en
The double-edged sword of autophagy modulation in cancer.
@nl
prefLabel
The double-edged sword of autophagy modulation in cancer.
@en
The double-edged sword of autophagy modulation in cancer.
@nl
P2860
P1476
The double-edged sword of autophagy modulation in cancer.
@en
P2093
Robert S DiPaola
P2860
P304
P356
10.1158/1078-0432.CCR-07-5023
P407
P50
P577
2009-08-25T00:00:00Z