S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.
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Sequence of full length cDNA for human S-adenosylhomocysteine hydrolaseAffinity-chromatographic purification of S-adenosyl-L-homocysteine hydrolase. Some properties of the enzyme from rat liverCovalent labelling of ligand binding sites of human placental S-adenosylhomocysteine hydrolase with 8-azido derivatives of adenosine and cyclic AMPEffect of analogues of 5'-methylthioadenosine on cellular metabolism. Inactivation of S-adenosylhomocysteine hydrolase by 5'-isobutylthioadenosineMolecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics.p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.Mechanism of deoxyadenosine-induced catabolism of adenine ribonucleotides in adenosine deaminase-inhibited human T lymphoblastoid cellsPossible metabolic basis for the different immunodeficient states associated with genetic deficiencies of adenosine deaminase and purine nucleoside phosphorylaseTranscription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteineResistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.ATP depletion as a consequence of adenosine deaminase inhibition in man.Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.Proposed explanation for S-adenosylhomocysteine hydrolase deficiency in purine nucleoside phosphorylase and hypoxanthine-guanine phosphoribosyltransferase-deficient patientsInactivation of S-adenosylhomocysteine hydrolase during adenine arabinoside therapyRestoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinasesEvidence for a substrate cycle between AMP and adenosine in isolated hepatocytes.The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene.Homocysteine Metabolism, Atherosclerosis, and Diseases of Aging.Transmethylation inhibitors decrease chemotactic sensitivity and delay cell aggregation in Dictyostelium discoideum.Inactivation of liver S-adenosylhomocysteine hydrolase in vitro of rats treated with erythro-9-(2-hydroxynon-3-yl)adenine.S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization.Family and population studies of SAHH and ADA polymorphisms. A possible pitfall in the ascertainment of SAHH electrophoretic phenotypes.
P2860
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P2860
S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1979
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@en
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@nl
type
label
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@en
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@nl
prefLabel
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@en
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@nl
P2860
P356
P1476
S-adenosylhomocysteine toxicit ...... lymphoblasts of human origin.
@en
P2093
Hershfield MS
Kredich NM
P2860
P304
P356
10.1073/PNAS.76.5.2450
P407
P577
1979-05-01T00:00:00Z