p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.
about
Point mutations at the purine nucleoside phosphorylase locus impair thymocyte differentiation in the mouseAdenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signalingMetabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstructionMitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient micepolyethylene glycol-conjugated adenosine deaminase (ADA) therapy provides temporary immune reconstitution to a child with delayed-onset ADA deficiencyCarrier frequency of a nonsense mutation in the adenosine deaminase (ADA) gene implies a high incidence of ADA-deficient severe combined immunodeficiency (SCID) in Somalia and a single, common haplotype indicates common ancestry.The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: the Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency.Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes.Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients.Hypoxia induces T-cell apoptosis by inhibiting chemokine C receptor 7 expression: the role of adenosine receptor A(2).Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target.Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients.Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 1. Dose-response analysis.Antioxidants modulate adenosine metabolism in rat mesangial cells cultured under high glucose conditions.Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Molecular Pathogenesis and Clinical Manifestations.The role of interleukin-7 in early T-cell development.
P2860
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P2860
p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
p53 expression is required for ...... denosine deaminase deficiency.
@ast
p53 expression is required for ...... denosine deaminase deficiency.
@en
type
label
p53 expression is required for ...... denosine deaminase deficiency.
@ast
p53 expression is required for ...... denosine deaminase deficiency.
@en
prefLabel
p53 expression is required for ...... denosine deaminase deficiency.
@ast
p53 expression is required for ...... denosine deaminase deficiency.
@en
P2860
P356
P1476
p53 expression is required for ...... adenosine deaminase deficiency
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.18.8373
P407
P577
1995-08-01T00:00:00Z