A role for CD47 in the development of experimental colitis mediated by SIRPalpha+CD103- dendritic cells.
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Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitisEndothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivoOsteopontin expression by CD103- dendritic cells drives intestinal inflammationType I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity.Microbial control of regulatory and effector T cell responses in the gut.Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activationNovel role of CD47 in rat microvascular endothelium: signaling and regulation of T-cell transendothelial migration.CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapyCD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis.Neonatal colonisation expands a specific intestinal antigen-presenting cell subset prior to CD4 T-cell expansion, without altering T-cell repertoire.Microbe-dendritic cell dialog controls regulatory T-cell fate.CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production.Thrombospondin-1 is a CD47-dependent endogenous inhibitor of hydrogen sulfide signaling in T cell activationCd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells.CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functionsDendritic cells in oral tolerance in the gut.Dendritic cells in bacteria handling in the gut.Experimental models to investigate the function of dendritic cell subsets: challenges and implications.The CD47-SIRPα signalling system: its physiological roles and therapeutic application.The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propriaCD47 fusion protein targets CD172a+ cells in Crohn's disease and dampens the production of IL-1β and TNFDonor SIRPα polymorphism modulates the innate immune response to allogeneic grafts.E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis.Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells.CD47 deficiency does not impede polymorphonuclear neutrophil transmigration but attenuates granulopoiesis at the postacute stage of colitis.Induction of murine TNBS colitis is strictly controlled by a modified method using continuous inhalation anesthesia with sevoflurane.Topoisomerase I peptide-loaded dendritic cells induce autoantibody response as well as skin and lung fibrosis.Association of the protein-tyrosine phosphatase nonreceptor type substrate 1 (PTPNS1) gene with inflammatory bowel disease.CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma.CD47
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A role for CD47 in the development of experimental colitis mediated by SIRPalpha+CD103- dendritic cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@en
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@nl
type
label
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@en
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@nl
prefLabel
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@en
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@nl
P2093
P2860
P356
P1476
A role for CD47 in the develop ...... Palpha+CD103- dendritic cells.
@en
P2093
Denis Franchimont
Genevieve Fortin
Manuel Rubio
Marianne Raymond
Marika Sarfati
Patrick Gautier
Vu Quang Van
P2860
P304
P356
10.1084/JEM.20082805
P407
P577
2009-08-24T00:00:00Z