Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin.
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Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structureCloning and characterization of HuR, a ubiquitously expressed Elav-like proteinInteractions between the aryl hydrocarbon receptor and P-TEFb. Sequential recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoterExpression and characterization of recombinant caveolin. Purification by polyhistidine tagging and cholesterol-dependent incorporation into defined lipid membranesDioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcriptionMechanism of dioxin action: receptor-enhancer interactions in intact cellsGlucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complexcAMP-dependent negative regulation of rat aldehyde dehydrogenase class 3 gene expressionChromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activationDifferential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines.Structural and functional cross-talk between a distant enhancer and the epsilon-globin gene promoter shows interdependence of the two elements in chromatin.The 2001 Veylien Henderson Award of the Society of Toxicology of Canada. Positive and negative transcriptional regulation of cytochromes P450 by polycyclic aromatic hydrocarbons.Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryos.Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuliToxicogenomic profiles in relation to maternal immunotoxic exposure and immune functionality in newborns.The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxinTransactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo.A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter.Repression of dioxin signal transduction in fibroblasts. Identification Of a putative repressor associated with Arnt.Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter.HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation.Role of mediator in transcriptional activation by the aryl hydrocarbon receptor.Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex.Aryl hydrocarbon receptor-mediated signal transduction.Induction of drug-metabolizing enzymes by dioxin.Transcriptional activation by the mouse Ah receptor. Interplay between multiple stimulatory and inhibitory functions.Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses.Chromatin remodeling by the thyroid hormone receptor in regulation of the thyroid-stimulating hormone alpha-subunit promoter.
P2860
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P2860
Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Transcription-dependent and tr ...... disruption induced by dioxin.
@en
Transcription-dependent and tr ...... disruption induced by dioxin.
@nl
type
label
Transcription-dependent and tr ...... disruption induced by dioxin.
@en
Transcription-dependent and tr ...... disruption induced by dioxin.
@nl
prefLabel
Transcription-dependent and tr ...... disruption induced by dioxin.
@en
Transcription-dependent and tr ...... disruption induced by dioxin.
@nl
P2860
P356
P1476
Transcription-dependent and tr ...... disruption induced by dioxin.
@en
P2093
J E Morgan
J P Whitlock
P2860
P304
11622-11626
P356
10.1073/PNAS.89.23.11622
P407
P577
1992-12-01T00:00:00Z