Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations?
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Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancyAntibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines?High-dose continuous oxacillin infusion results in achievement of pharmacokinetics targets in critically ill patients with deep sternal wound infections following cardiac surgery.Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions.Impact of hypoalbuminemia on voriconazole pharmacokinetics in critically ill adult patients.How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patientsTherapeutic drug monitoring: linezolid too?Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignanciesProtein binding characteristics and pharmacokinetics of ceftriaxone in intensive care unit patientsAugmented renal clearance implies a need for increased amoxicillin-clavulanic acid dosing in critically ill children.Population Pharmacokinetics of Doripenem in Critically Ill Patients with Sepsis in a Malaysian Intensive Care Unit.In Vivo Microdialysis To Determine Subcutaneous Interstitial Fluid Penetration and Pharmacokinetics of Fluconazole in Intensive Care Unit Patients with Sepsis.Piperacillin concentration in relation to therapeutic range in critically ill patients--a prospective observational study.We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?Pharmacokinetics of Piperacillin in Critically Ill Australian Indigenous Patients with Severe Sepsis.Clinical outcomes of extended versus intermittent administration of piperacillin/tazobactam for the treatment of hospital-acquired pneumonia: a randomized controlled trial.Using Population Pharmacokinetic Modeling and Monte Carlo Simulations To Determine whether Standard Doses of Piperacillin in Piperacillin-Tazobactam Regimens Are Adequate for the Management of Febrile Neutropenia.Extended infusion of beta-lactam antibiotics: optimizing therapy in critically-ill patients in the era of antimicrobial resistance.Therapeutic drug monitoring of anti-infective agents in critically ill patients.High target attainment for β-lactam antibiotics in intensive care unit patients when actual minimum inhibitory concentrations are applied.Dose optimization of piperacillin/tazobactam in critically ill children.Optimizing β-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?Early Hypoalbuminemia is an Independent Predictor of Mortality in Aneurysmal Subarachnoid Hemorrhage.Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial.What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?[Therapeutic drug monitoring and individual dosing of antibiotics during sepsis : Modern or just "trendy"?]Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project.Pharmacokinetics of an extended 4-hour infusion of piperacillin-tazobactam in critically ill patients undergoing continuous renal replacement therapy.An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units.Pharmacokinetics and Pharmacodynamic Target Attainment of Benzylpenicillin in an Adult Severely ill Sub-Saharan African Patient Population.Electrokinetic Size and Mobility Traps for On-site Therapeutic Drug Monitoring.Considerable variation of trough β-lactam concentrations in older adults hospitalized with infection-a prospective observational study.Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures.Population Pharmacokinetic Model for Cefuroxime Used in Coronary Artery Bypass Graft Surgery with Cardiopulmonary Bypass: Model-Based Evaluation of Standard Dosing Regimens.Liquid chromatography–tandem mass spectrometry for the simultaneous quantitation of ceftriaxone, metronidazole and hydroxymetronidazole in plasma from seriously ill, severely malnourished children.Piperacillin population pharmacokinetics in critically ill patients with multiple organ dysfunction syndrome receiving continuous venovenous haemodiafiltration: effect of type of dialysis membrane on dosing requirements.[Pharmacokinetics and pharmacodynamics of antibiotics in intensive care].Translational Modeling of Antibacterial AgentsTraining a Drug to Do New Tricks: Insights on Stability of Meropenem Administered as a Continuous Infusion
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Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Protein binding of β-lactam an ...... redict unbound concentrations?
@en
Protein binding of β-lactam an ...... redict unbound concentrations?
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type
label
Protein binding of β-lactam an ...... redict unbound concentrations?
@en
Protein binding of β-lactam an ...... redict unbound concentrations?
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prefLabel
Protein binding of β-lactam an ...... redict unbound concentrations?
@en
Protein binding of β-lactam an ...... redict unbound concentrations?
@nl
P2093
P2860
P50
P356
P1476
Protein binding of β-lactam an ...... redict unbound concentrations?
@en
P2093
Brett McWhinney
Scott Briscoe
Syamhanin Adnan
P2860
P304
P356
10.1128/AAC.00951-13
P407
P577
2013-09-30T00:00:00Z