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Improved Diagnostic Performance of High-Sensitivity Cardiac Troponin Assays Is an Artifact of Censored Data.Is high-dose β-lactam therapy associated with excessive drug toxicity in critically ill patients?Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkersSYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trialSynbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial.Use of plasma metanephrine to aid adrenal venous sampling in combined aldosterone and cortisol over-secretion.Bronchiectasis exacerbation study on azithromycin and amoxycillin-clavulanate for respiratory exacerbations in children (BEST-2): study protocol for a randomized controlled trial.A Protocol for the Pharmacokinetics of Enteric Coated Mycophenolate Sodium in Lupus Nephritis (POEMSLUN): an open-label, randomised controlled trialProtein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations?Sex Hormone Binding Globulin Modifies Testosterone Action and Metabolism in Prostate Cancer CellsFalsely elevated troponin I results due to outliers indicate a lack of analytical robustness.The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease.Mind the gap: Shortcomings of the osmotic gap and a possible solution.Ethambutol Is Cleared by a Contemporary High-Flux Hemodialyzer, and Drug Monitoring Ensures Safety and Therapeutic Effect.Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy.Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery.Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU.β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia.Glucocorticoid Sensitivity Is Highly Variable in Critically Ill Patients With Septic Shock and Is Associated With Disease Severity.Adenosine deaminase isoenzymes in typhoid fever.Even high-dose extended infusions may not yield desired concentrations of β-lactams: the value of therapeutic drug monitoring.Policy change to improve pathology turnaround time and reduce costs--possible to do both?Delta troponin for the early diagnosis of AMI in emergency patients with chest pain.Biological and diurnal variation in glucocorticoid sensitivity detected with a sensitive in vitro dexamethasone suppression of cytokine production assay.ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity.Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept.Gonadotrophin-independent precocious puberty in an eight-year-old boy due to ectopic human chorionic gonadotrophin from the central nervous system.Neonatal complete generalized glucocorticoid resistance and growth hormone deficiency caused by a novel homozygous mutation in Helix 12 of the ligand binding domain of the glucocorticoid receptor gene (NR3C1).A case of discordant HbA(1c): a method-dependent error.Significance of cerebrospinal fluid adenosine deaminase isoenzymes in tuberculous (TB) meningitis.A differential impact of mycophenolic acid, prednisolone, and tacrolimus exposure on sCD30 levels in adult kidney transplant recipients.A fit-for-purpose approach to analytical sensitivity applied to a cardiac troponin assay: time to escape the 'highly-sensitive' trap.Performance of risk stratification for acute coronary syndrome with two-hour sensitive troponin assay results.NR1I2 polymorphisms are related to tacrolimus dose-adjusted exposure and BK viremia in adult kidney transplantation.Measurement of cortisol, cortisone, prednisolone, dexamethasone and 11-deoxycortisol with ultra high performance liquid chromatography-tandem mass spectrometry: Application for plasma, plasma ultrafiltrate, urine and saliva in a routine laboratory.Serial changes in plasma total cortisol, plasma free cortisol, and tissue cortisol activity in patients with septic shock: an observational study.Response to Basu et al.Concordance, variance, and outliers in 4 contemporary cardiac troponin assays: implications for harmonization.Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests.
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P50
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wetenschapper
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հետազոտող
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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Jacobus Ungerer
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0000-0003-4929-0929