Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis
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Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticalsMorin exerts neuroprotective actions in Parkinson disease models in vitro and in vivo.Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.Morin, a flavonoid from moraceae, induces apoptosis by induction of BAD protein in human leukemic cells.Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascadeCancer and diet: How are they related?Preclinical cancer chemoprevention studies using animal model of inflammation-associated colorectal carcinogenesis.Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase.Morin hydrate promotes inner ear neural stem cell survival and differentiation and protects cochlea against neuronal hearing loss.Effects of flavonoids and other polyphenols on inflammation.Natural and Synthetic Flavonoids: Structure-Activity Relationship and Chemotherapeutic Potential for the Treatment of Leukemia.Preparation, in vitro and in vivo evaluation of polymeric nanoparticles based on hyaluronic acid-poly(butyl cyanoacrylate) and D-alpha-tocopheryl polyethylene glycol 1000 succinate for tumor-targeted delivery of morin hydrate.Anti-inflammatory effects of kolaviron modulate the expressions of inflammatory marker genes, inhibit transcription factors ERK1/2, p-JNK, NF-κB, and activate Akt expressions in the 93RS2 Sertoli cell lines.Morin modulates the oxidative stress-induced NF-kappaB pathway through its anti-oxidant activity.Morin hydrate attenuates the acrylamide-induced imbalance in antioxidant enzymes in a murine modelThe anti-inflammatory effects of Morin hydrate in atherosclerosis is associated with autophagy induction through cAMP signaling.Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway.Flavonoid, morin inhibits oxidative stress, inflammation and enhances neurotrophic support in the brain of streptozotocin-induced diabetic rats.Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage via inhibiting the nuclear transcription factor kappa β-related pathway in rats.
P2860
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P2860
Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Morin (3,5,7,2',4'-Pentahydrox ...... and up-regulation of apoptosis
@en
Morin (3,5,7,2',4'-Pentahydrox ...... nd up-regulation of apoptosis.
@nl
type
label
Morin (3,5,7,2',4'-Pentahydrox ...... and up-regulation of apoptosis
@en
Morin (3,5,7,2',4'-Pentahydrox ...... nd up-regulation of apoptosis.
@nl
prefLabel
Morin (3,5,7,2',4'-Pentahydrox ...... and up-regulation of apoptosis
@en
Morin (3,5,7,2',4'-Pentahydrox ...... nd up-regulation of apoptosis.
@nl
P2093
P2860
P1476
Morin (3,5,7,2',4'-Pentahydrox ...... and up-regulation of apoptosis
@en
P2093
Bharat B Aggarwal
Govindarajan T Ramesh
Rishi S Aggarwal
Sunil K Manna
P2860
P304
P356
10.1158/1078-0432.CCR-06-2394
P407
P50
P577
2007-04-01T00:00:00Z