about
Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathwayAnticancer properties of nimbolide and pharmacokinetic considerations to accelerate its developmentTargeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and PerspectivesUrsolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cellsExosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from ImmunosurveillanceTargeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solutionThe vascular endothelium and human diseasesIdentification of a novel Calotropis procera protein that can suppress tumor growth in breast cancer through the suppression of NF-κB pathwayThymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROSDes-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of ActionTrisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling PathwayChalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cellsInhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancerMelioidosis: Clinical impact and public health threat in the tropics.Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades.Novel medicines and strategies in cancer treatment and preventionPotential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators.TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activationDEAD-box helicase DP103 defines metastatic potential of human breast cancers.Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-ATUrsolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathwaysNegative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathwayAnti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives.Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives.Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo.Curcumin: getting back to the roots.Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinomaDevelopment of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivoThe multifaceted role of curcumin in cancer prevention and treatment.Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apAnnexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.Wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus)Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4Identification of novel peroxisome proliferator-activated receptor-gamma (PPARγ) agonists using molecular modeling method.Natural bioactives in cancer treatment and prevention.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Gautam Sethi
@ast
Gautam Sethi
@en
Gautam Sethi
@es
Gautam Sethi
@nl
Gautam Sethi
@sl
type
label
Gautam Sethi
@ast
Gautam Sethi
@en
Gautam Sethi
@es
Gautam Sethi
@nl
Gautam Sethi
@sl
prefLabel
Gautam Sethi
@ast
Gautam Sethi
@en
Gautam Sethi
@es
Gautam Sethi
@nl
Gautam Sethi
@sl
P106
P31
P496
0000-0002-8677-8475