Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
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Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infectionThe SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDLMammalian lipoxygenases and their biological relevanceFunctional and pathological roles of the 12- and 15-lipoxygenasesPolyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages.Emerging targets in lipid-based therapyPolyunsaturated fatty acids and cardiovascular disease: implications for nutrigeneticsAP-1 (Fra-1/c-Jun)-mediated induction of expression of matrix metalloproteinase-2 is required for 15S-hydroxyeicosatetraenoic acid-induced angiogenesis.Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins.Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects.ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15(S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formationBiological properties of apolipoprotein a-I mimetic peptides.12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation.Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice.Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway.Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease.The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis5-Lipoxygenase inhibitors: a review of recent developments and patents.Toll-like receptor-4 and lipoprotein accumulation in macrophagesEicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke.Role of phospholipid oxidation products in atherosclerosis.5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).Molecular biology of atherosclerosis.Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.Myeloid cell 5-lipoxygenase activating protein modulates the response to vascular injury.12/15-Lipoxygenase deficiency reduces densities of mesenchymal stem cells in the dermis of wounded and unwounded skinMice deficient in L-12/15 lipoxygenase show increased vulnerability to 3-nitropropionic acid neurotoxicity.Role of 15-hydroxyeicosatetraenoic acid in hemozoin-induced lysozyme release from human adherent monocytes.
P2860
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P2860
Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@en
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@nl
type
label
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@en
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@nl
prefLabel
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@en
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@nl
P2860
P356
P1476
Dual 12/15- and 5-lipoxygenase ...... erosis in ApoE knock-out mice.
@en
P2093
Daniel Poeckel
Karin A Zemski Berry
P2860
P304
21077-21089
P356
10.1074/JBC.M109.000901
P407
P577
2009-06-09T00:00:00Z