An essential role for the IL-2 receptor in Treg cell function. - Wikidata - awgldk - TriplyDB

An essential role for the IL-2 receptor in Treg cell function.

An essential role for the IL-2 receptor in Treg cell function.

http://www.wikidata.org/entity/Q37351745

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Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy.mTOR regulates neuroprotective effect of immunized CD4+Foxp3+ T cells in optic nerve ischemia.Direct control of regulatory T cells by keratinocytes.The Lower Limit of Regulatory CD4+ Foxp3+ TCRβ Repertoire Diversity Required To Control Autoimmunity.Regulatory T Cells: Differentiation and Function.Mechanistic approaches for the prevention and treatment of chronic GVHD.Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model.STAT5 and CD4 + T Cell Immunity.IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes.Metabolism in Immune Cell Differentiation and Function.Immune modulation by curcumin: The role of interleukin-10.Neoantigen Expression in Steady-State Langerhans Cells Induces CTL Tolerance.Humoral Immunodeficiency with Hypotonia, Feeding Difficulties, Enteropathy, and Mild Eczema Caused by a Classical FOXP3 Mutation.TCR Signaling and CD28/CTLA-4 Signaling Cooperatively Modulate T Regulatory Cell Homeostasis.Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells.Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells.Functional heterogeneity of gut-resident regulatory T cells.Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.Regulatory T cells in Acute and Chronic Kidney Diseases.Virologic and Immunologic Characteristics in Mature Ducks with Acute Duck Hepatitis A Virus 1 Infection.IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level.Regulatory T cells characterized by low Id3 expression are highly suppressive and accumulate during chronic infection.Harnessing the power of regulatory T-cells to control autoimmune diabetes: overview and perspective.Altered homeostasis and development of regulatory T cell subsets represent an IL-2R-dependent risk for diabetes in NOD mice.An increased CD25-positive intestinal regulatory T lymphocyte population is dependent upon Cox-2 activity in the Apcmin/+ model.Lymphocytes in Placental Tissues: Immune Regulation and Translational Possibilities for Immunotherapy.CD11a/ICAM-1 blockade combined with IL-2 targeting therapy causes a paradoxical acceleration of type 1 diabetes.New and emerging therapies for acute and chronic graft versus host disease.Regulatory T cells in retroviral infections.Immunometabolism and PI(3)K Signaling As a Link between IL-2, Foxp3 Expression, and Suppressor Function in Regulatory T Cells.Genome-wide association studies in Crohn's disease: Past, present and future.An attempt to induce an immunomodulatory effect in rowers with spirulina extract.Combination Immunotherapy: Taking Cancer Vaccines to the Next Level.IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner.LFA-1 in T Cell Migration and Differentiation.Emerging Functions of Regulatory T Cells in Tissue Homeostasis.Efficacy of T Regulatory Cells, Th17 Cells and the Associated Markers in Monitoring Tuberculosis Treatment Response.Autoimmune Lymphoproliferative Syndrome-FAS Patients Have an Abnormal Regulatory T Cell (Treg) Phenotype but Display Normal Natural Treg-Suppressive Function on T Cell Proliferation.Foxp3+ T Regulatory Cells: Still Many Unanswered Questions-A Perspective After 20 Years of Study.Inducible T-Cell Co-Stimulator Impacts Chronic Graft-Versus-Host Disease by Regulating Both Pathogenic and Regulatory T Cells.

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An essential role for the IL-2 receptor in Treg cell function.

http://www.wikidata.org/entity/Q37351745

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 05 September 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

An essential role for the IL-2 receptor in Treg cell function.

@en

An essential role for the IL-2 receptor in Treg cell function.

@nl

type

label

An essential role for the IL-2 receptor in Treg cell function.

@en

An essential role for the IL-2 receptor in Treg cell function.

@nl

prefLabel

An essential role for the IL-2 receptor in Treg cell function.

@en

An essential role for the IL-2 receptor in Treg cell function.

@nl

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Nature Immunology

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An essential role for the IL-2 receptor in Treg cell function.

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Alexander Y Rudensky

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Andrew G Levine

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Arun K Kannan

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Jason D Fontenot

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Takatoshi Chinen

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Ulf Klein

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Xiying Fan

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Ye Zheng

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Yongqiang Feng

http://www.w3.org/2001/XMLSchema#string

P2860

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

Control of regulatory T cell development by the transcription factor Foxp3

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

A function for interleukin 2 in Foxp3-expressing regulatory T cells

Trimmomatic: a flexible trimmer for Illumina sequence data

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

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1322-1333

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scholarly article

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10.1038/NI.3540

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11

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17

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Georg Gasteiger

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2016-09-05T00:00:00Z

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1030227951

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27595233

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5071159

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