Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.

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Interactions Between the Neuroendocrine System and T Lymphocytes in Diabetes.

P2860

Q55337327-8D33C39D-C01B-4751-93E1-46F0B0160C08

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Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.

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Attenuated IL-2R signaling in ...... dependent on activation state.

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Attenuated IL-2R signaling in ...... dependent on activation state.

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Attenuated IL-2R signaling in ...... dependent on activation state.

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Attenuated IL-2R signaling in ...... dependent on activation state.

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Attenuated IL-2R signaling in ...... dependent on activation state.

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Attenuated IL-2R signaling in ...... dependent on activation state.

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P1476

Attenuated IL-2R signaling in ...... dependent on activation state

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P2093

Carla Greenbaum

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Cate Speake

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Jane Buckner

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Jerill Thorpe

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Karen Cerosaletti

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Katharine Schwedhelm

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Marc Gavin

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Sara A Murray

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P2860

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study

Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects

New insights into the regulation of T cells by gamma(c) family cytokines

Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammation

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival.

A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells.

Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes

The biology of interleukin-2.

An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells.

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67-74

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scholarly article

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10.1016/J.CLIM.2017.06.004

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181

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S Alice Long

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2017-06-20T00:00:00Z

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28645874

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5564451

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Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.

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P2860

P2860

Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.

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P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932