Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
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Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic AgentsThe tandem PH domain-containing protein 2 (TAPP2) regulates chemokine-induced cytoskeletal reorganization and malignant B cell migrationCXCR4 over-expression and survival in cancer: a system review and meta-analysisLoss of PTEN permits CXCR4-mediated tumorigenesis through ERK1/2 in prostate cancer cellsChitosan promotes cancer progression and stem cell properties in association with Wnt signaling in colon and hepatocellular carcinoma cells.Anti-HIV small-molecule binding in the peptide subpocket of the CXCR4:CVX15 crystal structure.Peptide-based probes for targeted molecular imaging.CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomographyCXCR4 pathway associated with family history of melanoma.Bridged cyclams as imaging agents for chemokine receptor 4 (CXCR4)CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy.CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis.Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.The emerging role of CXC chemokines and their receptors in cancer.Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trialsStromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells.CXCL12/CXCR4 blockade by oncolytic virotherapy inhibits ovarian cancer growth by decreasing immunosuppression and targeting cancer-initiating cells.Small molecule inhibitors of CXCR4.Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CTDiscovery and computer aided potency optimization of a novel class of small molecule CXCR4 antagonists.The intricate role of CXCR4 in cancer.Novel therapeutics for aggressive non-Hodgkin's lymphoma.Imaging CXCR4 expression in human cancer xenografts: evaluation of monocyclam 64Cu-AMD3465.Therapeutic targets for bone metastases in breast cancer.Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7.Bone Targeted Therapies for Bone Metastasis in Breast CancerBone-Targeted Agents for the Management of Breast Cancer Patients with Bone MetastasesStroma targeting nuclear imaging and radiopharmaceuticals.Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model.Prognostic significance of CXCL12, CXCR4, and CXCR7 in patients with breast cancer.Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastasesSDF1/CXCL12 is involved in recruitment of stem-like progenitor cells to orthotopic murine malignant mesothelioma spheroidsThe significance of macrophage phenotype in cancer and biomaterials.CXCL12/CXCR4 signal axis plays an important role in mediating bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells.The influence of tumor-host interactions in the stromal cell-derived factor-1/CXCR4 ligand/receptor axis in determining metastatic risk in breast cancer.Multimodality imaging of CXCR4 in cancer: current status towards clinical translation.Optimal management of bone metastases in breast cancer patients.Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy.Targeting the CXCR4/CXCL12 axis in systemic lupus erythematosus.
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Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@en
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@nl
type
label
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@en
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@nl
prefLabel
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@en
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@nl
P1476
Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside.
@en
P2093
Donald Wong
Walter Korz
P304
P356
10.1158/1078-0432.CCR-07-4846
P407
P577
2008-12-01T00:00:00Z