The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons.
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Maintenance of postmitotic neuronal cell identityMaintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiologyThe bHLH Transcription Factor Hand Regulates the Expression of Genes Critical to Heart and Muscle Function in Drosophila melanogasterTargeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract developmentSequential requirement of Sox4 and Sox11 during development of the sympathetic nervous systemExpression of sympathetic nervous system genes in Lamprey suggests their recruitment for specification of a new vertebrate featureDevelopmental transcriptional networks are required to maintain neuronal subtype identity in the mature nervous system.Cytokines inhibit norepinephrine transporter expression by decreasing Hand2Satb2-independent acquisition of the cholinergic sudomotor phenotype in rodents.Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis.Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthoodA Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis.Autonomic cardiac innervation: development and adult plasticity.Transcriptional control of differentiation and neurogenesis in autonomic ganglia.Ontogeny of cardiac sympathetic innervation and its implications for cardiac disease.The neural crest: a versatile organ system.The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.Cortical gene expression in spinal cord injury and repair: insight into the functional complexity of the neural regeneration program.Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal deathModulation of dopamine-dependent behaviors by the Caenorhabditis elegans Olig homolog HLH-17.Coordinate expression of pan-neuronal and functional signature genes in sympathetic neurons.Distinct roles of hand2 in developing and adult autonomic neurons.Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons.Part and Parcel of the Cardiac Autonomic Nerve System: Unravelling Its Cellular Building Blocks during Development.From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development.Sympathetic tales: subdivisons of the autonomic nervous system and the impact of developmental studies
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P2860
The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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The bHLH transcription factor ...... rentiated sympathetic neurons.
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The bHLH transcription factor ...... rentiated sympathetic neurons.
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The bHLH transcription factor ...... rentiated sympathetic neurons.
@en
The bHLH transcription factor ...... rentiated sympathetic neurons.
@nl
prefLabel
The bHLH transcription factor ...... rentiated sympathetic neurons.
@en
The bHLH transcription factor ...... rentiated sympathetic neurons.
@nl
P2093
P2860
P1476
The bHLH transcription factor ...... rentiated sympathetic neurons.
@en
P2093
Hermann Rohrer
Kazuto Kobayashi
Manuela Pape
Marthe J Howard
Matthias Stanke
Mirko Schmidt
Shengyin Lin
Uwe Ernsberger
P2860
P304
P356
10.1016/J.YDBIO.2009.02.020
P407
P577
2009-02-27T00:00:00Z