The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth - Wikidata - awgldk - TriplyDB

The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth

The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth

http://www.wikidata.org/entity/Q37353804

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WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity Wnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritis Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets Pentoxifylline Inhibits WNT Signalling in β-Cateninhigh Patient-Derived Melanoma Cell Populations Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma Investigating microenvironmental regulation of human chordoma cell behaviour Hypoxia, inflammation, and the tumor microenvironment in metastatic disease The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma miR-205 expression promotes cell proliferation and migration of human cervical cancer cells Structural ECM components in the premetastatic and metastatic niche.MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor Cooperative interaction of CTGF and TGF-β in animal models of fibrotic disease.The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes Reduced CTGF expression promotes cell growth, migration, and invasion in nasopharyngeal carcinoma WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone.Downregulation of connective tissue growth factor inhibits the growth and invasion of gastric cancer cells and attenuates peritoneal dissemination Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.Potential prognostic biomarkers for bone metastasis from hepatocellular carcinoma.TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade.Connective tissue growth factor is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth.Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer Differential expression of CCN family members CYR611, CTGF and NOV in gastric cancer and their association with disease progression P38 pathway as a key downstream signal of connective tissue growth factor to regulate metastatic potential in non-small-cell lung cancer.Novel agents for the treatment of adenocarcinoma of the pancreas.Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth.CTGF is a therapeutic target for metastatic melanoma.Novel therapeutic strategies targeting tumor-stromal interactions in pancreatic cancer.Inflammation and pancreatic cancer: disease promoter and new therapeutic target.Selected terpenoids from medicinal plants modulate endoplasmic reticulum stress in metabolic disorders.Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer.The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?

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The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth

http://www.wikidata.org/entity/Q37353804

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article científic

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article scientifique

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artigo científico

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bilimsel makale

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scientific article published on February 2009

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name

The role of tumor cell-derived ...... N2) in pancreatic tumor growth

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The role of tumor cell-derived connective tissue growth factor

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The role of tumor cell-derived ...... N2) in pancreatic tumor growth

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The role of tumor cell-derived ...... N2) in pancreatic tumor growth

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0008-5472.CAN-08-0987

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Cancer Research

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The role of tumor cell-derived ...... N2) in pancreatic tumor growth

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Amato J Giaccia

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Christine M Ham

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Edward E Graves

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George P Yang

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Jonathan Feazell

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Kevin L Bennewith

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Neeraja Kambham

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Xin Huang

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P2860

Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

Cancer statistics, 2008

All in the CCN family: essential matricellular signaling modulators emerge from the bunker

Connective tissue growth factor is involved in pancreatic repair and tissue remodeling in human and rat acute necrotizing pancreatitis

NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues.

Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome

Pulmonary hypoplasia in the connective tissue growth factor (Ctgf) null mouse

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775-784

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scholarly article

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10.1158/0008-5472.CAN-08-0987

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3

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Janine Terra Erler

Albert C. Koong

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2009-02-01T00:00:00Z

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19179545

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connective tissue

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2747032

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