Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence
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Attenuation of the self-renewal of transit-amplifying osteoblast progenitors in the murine bone marrow by 17 beta-estradiolFrom estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosisThe estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical boneBeta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation.Hormone replacement therapy and fractures in older adults.The role of vitamin E in reversing bone loss.The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation.Hyperglycemia diverts dividing osteoblastic precursor cells to an adipogenic pathway and induces synthesis of a hyaluronan matrix that is adhesive for monocytesIndependent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia.Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormonePrevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitoninHormonal regulation of physiological cell turnover and apoptosis.Increased bone adiposity and peroxisomal proliferator-activated receptor-gamma2 expression in type I diabetic mice.Fat tissue, aging, and cellular senescence.Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in miceDisruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells.Aging and bone.Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways.Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression.PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors.A gene(s) for all-trans-retinoic acid-induced forelimb defects mapped and confirmed to murine chromosome 11Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment.Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasiaEffects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women.Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids.Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroidsEmodin enhances osteogenesis and inhibits adipogenesisEstrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalphaResolving the Two "Bony" Faces of PPAR-gamma.The Genetics of PPARG and the Skeleton.Spinal cord injury causes bone loss through peroxisome proliferator-activated receptor-γ and Wnt signallingTransplantation of mesenchymal stem cells from young donors delays aging in miceTGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor inductionBone is a target for the antidiabetic compound rosiglitazone.A novel locus on the X chromosome regulates post-maturity bone density changes in miceSuppression of zinc finger protein 467 alleviates osteoporosis through promoting differentiation of adipose derived stem cells to osteoblasts.The growth and age-related origins of bone fragility in men.Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice.Dysregulated in vitro hematopoiesis, radiosensitivity, proliferation, and osteoblastogenesis with marrow from SAMP6 mice.Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength.
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Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Linkage of decreased bone mass ...... odel of accelerated senescence
@en
Linkage of decreased bone mass ...... del of accelerated senescence.
@nl
type
label
Linkage of decreased bone mass ...... odel of accelerated senescence
@en
Linkage of decreased bone mass ...... del of accelerated senescence.
@nl
prefLabel
Linkage of decreased bone mass ...... odel of accelerated senescence
@en
Linkage of decreased bone mass ...... del of accelerated senescence.
@nl
P2093
P2860
P356
P1476
Linkage of decreased bone mass ...... odel of accelerated senescence
@en
P2093
A M Parfitt
K Takahashi
R S Weinstein
S C Manolagas
P2860
P304
P356
10.1172/JCI118600
P407
P577
1996-04-01T00:00:00Z