Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines.
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Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatmentInterface of signal transduction inhibition and immunotherapy in melanoma.Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancerSafe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cellsThe small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activityThe multifaceted role of curcumin in cancer prevention and treatment.Botanicals for the prevention and treatment of cutaneous melanoma.A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.Glucose-6-phosphate dehydrogenase and NADPH oxidase 4 control STAT3 activity in melanoma cells through a pathway involving reactive oxygen species, c-SRC and SHP2.NF-κB as potential target in the treatment of melanoma.Targeting drivers of melanoma with synthetic small molecules and phytochemicals.Cancer and diet: How are they related?Molecular changes induced by the curcumin analogue D6 in human melanoma cells.Pyridine analogues of curcumin exhibit high activity for inhibiting CWR-22Rv1 human prostate cancer cell growth and androgen receptor activation.Outpatient Follow-up and Secondary Prevention for Melanoma PatientsImmunosuppressive Effects of Natural α,β-Unsaturated Carbonyl-Based Compounds, and Their Analogs and Derivatives, on Immune Cells: A Review.Curcumin and omega-3 fatty acids enhance NK cell-induced apoptosis of pancreatic cancer cells but curcumin inhibits interferon-γ production: benefits of omega-3 with curcumin against cancer.Curcumin: A new candidate for melanoma therapy?Magnetic core-shell nanocapsules with dual-targeting capabilities and co-delivery of multiple drugs to treat brain gliomas.STAT3 targeting by polyphenols: Novel therapeutic strategy for melanoma.Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?Design, synthesis and bioevaluation of novel N-substituted-3,5-bis(arylidene)-4-piperidone derivatives as cytotoxic and antitumor agents with fluorescent properties.1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation.Development and evaluation of co-formulated docetaxel and curcumin biodegradable nanoparticles for parenteral administration.Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production.Curcumin and Melanoma: From Chemistry to Medicine.Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells.Co-Delivery of Curcumin and Chrysin by Polymeric Nanoparticles Inhibit Synergistically Growth and hTERT Gene Expression in Human Colorectal Cancer Cells.Exploring major signaling cascades in melanomagenesis: a rationale route for targetted skin cancer therapy
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Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
@en
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
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type
label
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
@en
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
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prefLabel
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
@en
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
@nl
P2093
P2860
P1476
Curcumin induces proapoptotic ...... o immunotherapeutic cytokines.
@en
P2093
Courtney Bakan
Don M Benson
Gregory B Lesinski
Gregory Young
James Fuchs
Matthew A Bill
P2860
P304
P356
10.1158/1535-7163.MCT-09-0377
P577
2009-09-01T00:00:00Z