FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
about
Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells.Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancerMetformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cellsApoptosis induction by MEK inhibition in human lung cancer cells is mediated by BimFOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer.High BIM mRNA levels are associated with longer survival in advanced gastric cancerEstrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells.FOXO1A is a target for HER2-overexpressing breast tumors.Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascadeActivation of FOXO3a suggests good prognosis of patients with radically resected gastric cancerSalinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the β-catenin/TCF complex association via FOXO3a activationMethylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition.FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role.Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance.Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and drug resistance.Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer.Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance.Involvement of Non-coding RNAs in Chemo- and Radioresistance of Colorectal Cancer.Chromatin status of apoptosis genes correlates with sensitivity to chemo-, immune- and radiation therapy in colorectal cancer cell lines.Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a.Inhibition of EGFR-induced glucose metabolism sensitizes chondrosarcoma cells to cisplatin.A novel cyclometallated Pt(II)-ferrocene complex induces nuclear FOXO3a localization and apoptosis and synergizes with cisplatin to inhibit lung cancer cell proliferation.FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis.Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer.Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells.The tumour suppressor FOXO3 is a key regulator of mantle cell lymphoma proliferation and survival.Oncogenic regulation of tumor metabolic reprogramming.The Bacterial Species Campylobacter jejuni Induce Diverse Innate Immune Responses in Human and Avian Intestinal Epithelial Cells.miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance.FOXO3 induces ubiquitylation of AKT through MUL1 regulation.Involvement of miR-155/FOXO3a and miR-222/PTEN in acquired radioresistance of colorectal cancer cell line.Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy.Proteasome inhibitor MG132 induces thyroid cancer cell apoptosis by modulating the activity of transcription factor FOXO3a.Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers.MicroRNA-155 increases colon cancer chemoresistance to cisplatin by targeting forkhead box O3.Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin.
P2860
Q27851964-279FB706-DF07-4A6B-953E-AC5FB8F3EF7EQ28475229-70099669-BA3A-4722-B29D-6D9F4BDBB002Q28539104-A5F5C84D-B2DA-475C-8279-A3F5D2BC916FQ28749134-7C53FC8E-9A39-4BC9-B593-621D32BA3C39Q32884377-B7001DC8-85ED-46A7-B2D4-8F5015936FC9Q33598008-9D070F03-6747-450F-94B5-667D5B5E5F3BQ33636941-693C8FBB-3223-43C0-B2D3-F1C8ACB9578DQ33959090-9678D2D3-81C6-409E-944E-A2B8D9A24A7CQ34789931-4ECDFFEA-6F8F-4E05-8E1B-8952EA323874Q35632231-9198FB56-CBAE-450B-901B-830E33B6D4D6Q35833001-C2C10905-0854-49CD-8CC7-34447403D91BQ36849537-61381F94-46BC-4579-8B1A-5DAF920867E7Q37040688-6F182432-54CE-4655-86E6-439C34F5C3CAQ38057689-72B1C4A5-E033-46F0-B4FD-E0DFB5A13533Q38109317-972454D2-C98D-4ACF-8DDE-F3930C595E5DQ38202873-7DF01A12-E9B8-433C-8728-5516D466F19DQ38270775-4C037D21-0DB1-499D-A774-BD5EFFB79A29Q38826542-AA6BAC65-6D3D-4F6F-842A-1B8ABC9519A9Q38949945-59CD253F-C371-4A30-87CF-D06FD749489BQ39000854-E6D37629-33D2-48A9-94E8-B5886755C21AQ39002643-562B5D37-1492-4DFD-B625-BBF66AA2B7BDQ39027495-FA27FB89-41EC-45C2-9C10-BF50B39FC8BDQ39129282-66F9B58E-0508-439A-8FB1-C90D9900FA4DQ39182864-5FA27AA2-59AF-4172-9A84-A6F0BAB0D0CEQ39222725-F0811D87-87A5-4101-B0DA-D54F5D31F22EQ39438964-888FE1A8-6F1F-4AA4-9F55-6445BF835A3CQ42321596-87259B50-9EDA-42D4-9AD4-BEA026F96BF0Q42369828-B035FEDA-4FE9-4278-BF30-496B0E05B9D0Q42921031-D2C41E2C-3204-4959-B476-1E59986AAF95Q47105200-878321AA-04D5-4B0B-A943-95FCD6FA0B57Q50209839-CD552B0C-CB8B-46DE-B99C-D44BE8C05759Q50315356-E2DF32C4-5420-4BC9-A5C1-8505C7F390DBQ51129826-BCBA91D8-4AC6-4B2E-9F39-B5C1F6C967DCQ53264975-E3C0D99C-9B10-4041-B8D9-3B0887ABEC74Q55079679-4A5151AE-1935-40C5-9682-D859F7E95768Q55519018-26D2183E-1928-4F71-9CEC-5CB19BDE0D1F
P2860
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
@en
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells.
@nl
type
label
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
@en
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells.
@nl
prefLabel
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
@en
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells.
@nl
P2860
P50
P1476
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
@en
P2093
Jon Clardy
P2860
P304
P356
10.1158/1535-7163.MCT-08-0398
P577
2008-10-01T00:00:00Z