The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.
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Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replicationSynthesis of nucleoside phosphate and phosphonate prodrugsDesign, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.Herpes simplex virus and HIV: genital infection synergy and novel approaches to dual prevention.Chemical Incorporation of Chain-Terminating Nucleoside Analogs as 3'-Blocking DNA Damage and Their Removal by Human ERCC1-XPF Endonuclease.Synthesis of novel nucleoside analogue phosphorothioamidate prodrugs and in vitro anticancer evaluation against RKO human colon carcinoma cells.Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis and biological evaluation of new acyclic nucleoside ProTides.Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2'-Deoxypseudoisocytidine.The DiPPro approach: synthesis, hydrolysis, and antiviral activity of lipophilic d4T diphosphate prodrugs.Efficient synthesis of exo-N-carbamoyl nucleosides: application to the synthesis of phosphoramidate prodrugs.Synthesis and anti-herpetic activity of phosphoramidate ProTides.Synthesis and biological evaluation of purine 2'-fluoro-2'-deoxyriboside ProTides as anti-influenza virus agents.Symmetrical diamidate prodrugs of nucleotide analogues for drug delivery.Amidate Prodrugs of Cyclic 9-()-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus ActivityDensity functional theory calculation of cyclic carboxylic phosphorus mixed anhydrides as possible intermediates in biochemical reactions: Implications for the Pro-Tide approach
P2860
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P2860
The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The application of phosphorami ...... r confers anti-HIV inhibition.
@en
The application of phosphorami ...... r confers anti-HIV inhibition.
@nl
type
label
The application of phosphorami ...... r confers anti-HIV inhibition.
@en
The application of phosphorami ...... r confers anti-HIV inhibition.
@nl
prefLabel
The application of phosphorami ...... r confers anti-HIV inhibition.
@en
The application of phosphorami ...... r confers anti-HIV inhibition.
@nl
P2093
P2860
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P1476
The application of phosphorami ...... ir confers anti-HIV inhibition
@en
P2093
Andrea Lisco
Christophe Vanpouille
Davide Carta
Jan Balzarini
Leonid Margolis
P2860
P304
P356
10.1021/JM9007856
P407
P577
2009-09-01T00:00:00Z