Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
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Post-translational regulation of endothelial nitric oxide synthase in vascular endotheliumTetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpressionAltered Nitric Oxide System in Cardiovascular and Renal DiseasesRole for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological HypercholesterolemiaPharmacology and Clinical Drug Candidates in Redox MedicineTocopherols in the Prevention and Treatment of Atherosclerosis and Related Cardiovascular DiseaseRecoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recyclingPrinciples of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in diseaseTargeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular DiseasesNitric oxide synthases: regulation and functionFree radical production by dysfunctional eNOSStructural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory proteinGTP cyclohydrolase 1 inhibition attenuates vasodilation and increases blood pressure in ratsThe mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory proteinThe ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping studyTetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia.NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy.L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin.Isolation, purification, and identification of an important pigment, sepiapterin, from integument of the lemon mutant of the silkworm, Bombyx moriTetrahydrobiopterin in cardiovascular health and disease.Hypoxia and reoxygenation induce endothelial nitric oxide synthase uncoupling in endothelial cells through tetrahydrobiopterin depletion and S-glutathionylation.Silent Partner in Blood Vessel Homeostasis? Pervasive Role of Nitric Oxide in Vascular Disease.Nitric oxide in the pathogenesis of vascular disease.Bacterial translocation in cirrhotic rats stimulates eNOS-derived NO production and impairs mesenteric vascular contractilitySystemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease.Adventures in vascular biology: a tale of two mediators.The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough.Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 miceTetrahydrobiopterin improves endothelial function in cardiovascular disease: a systematic reviewIncreasing muscle mass improves vascular function in obese (db/db) mice.Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db -/-) mice: role of decreased tetrahydrobiopterin bioavailabilityThe pathophysiology of erectile dysfunction related to endothelial dysfunction and mediators of vascular function.Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemiaMechanisms of oxidative stress and vascular dysfunction.Impaired systemic tetrahydrobiopterin bioavailability and increased dihydrobiopterin in adult falciparum malaria: association with disease severity, impaired microvascular function and increased endothelial activation.Gender bias in gastroparesis: is nitric oxide the answer?Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling.Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production.Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging.
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P2860
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
@en
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
@nl
type
label
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
@en
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
@nl
prefLabel
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
@en
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
@nl
P2093
P2860
P356
P1476
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
@en
P2093
Cosentino F
Erkelens W
Kastelein J
P2860
P356
10.1172/JCI119131
P407
P577
1997-01-01T00:00:00Z