Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.
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Coculture of bovine cartilage with synovium and fibrous joint capsule increases aggrecanase and matrix metalloproteinase activitySirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse modelSynoviocytes protect cartilage from the effects of injury in vitroSirt1-deficient mice exhibit an altered cartilage phenotypeSoft tissue knee injury with concomitant osteochondral fracture is associated with higher degree of acute joint inflammation.Proteases involved in cartilage matrix degradation in osteoarthritis.Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines.The effects of interleukin-1β in modulating osteoclast-conditioned medium's influence on gelatinases in chondrocytes through mitogen-activated protein kinases.Development of 3D hydrogel culture systems with on-demand cell separation.Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee.Comparison of the Effects of Interleukin-1 on Equine Articular Cartilage Explants and Cocultures of Osteochondral and Synovial Explants.In vitro evaluation of S-(+)-ibuprofen as drug candidate for intra-articular drug delivery system.Adamts5 (aggrecanase-2) is widely expressed in the mouse musculoskeletal system and is induced in specific regions of knee joint explants by inflammatory cytokines
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P2860
Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Co-culture of mechanically inj ...... increases ADAMTS5 production.
@en
Co-culture of mechanically inj ...... increases ADAMTS5 production.
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type
label
Co-culture of mechanically inj ...... increases ADAMTS5 production.
@en
Co-culture of mechanically inj ...... increases ADAMTS5 production.
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Co-culture of mechanically inj ...... increases ADAMTS5 production.
@en
Co-culture of mechanically inj ...... increases ADAMTS5 production.
@nl
P2093
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P1476
Co-culture of mechanically inj ...... d increases ADAMTS5 production
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P2093
A J Grodzinsky
C R Flannery
J B Fitzgerald
M A DiMicco
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P304
P356
10.1016/J.ABB.2009.07.006
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P577
2009-07-14T00:00:00Z