Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP - Wikidata - awgldk - TriplyDB

Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP

Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP

http://www.wikidata.org/entity/Q28244888

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A systems biology approach to synovial joint lubrication in health, injury, and disease Loading-Induced Heat-Shock Response in Bovine Intervertebral Disc Organ Culture Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytes Combining Targeted Metabolomic Data with a Model of Glucose Metabolism: Toward Progress in Chondrocyte Mechanotransduction.Molecular analysis of chondrocytes cultured in agarose in response to dynamic compression Alphav and beta1 integrins regulate dynamic compression-induced proteoglycan synthesis in 3D gel culture by distinct complementary pathways Self-assembling peptide hydrogels modulate in vitro chondrogenesis of bovine bone marrow stromal cells.Increased cyclooxygenase-2 expression and prostaglandin E2 production in pressurized renal medullary interstitial cells.Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs.Cyclic compressive loading on 3D tissue of human synovial fibroblasts upregulates prostaglandin E2 via COX-2 production without IL-1β and TNF-α In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis Periodic Nanomechanical Stimulation in a Biokinetics Model Identifying Anabolic and Catabolic Pathways Associated With Cartilage Matrix Homeostasis.A Distinct Catabolic to Anabolic Threshold Due to Single-Cell Static Nanomechanical Stimulation in a Cartilage Biokinetics Model The mechanobiology of articular cartilage: bearing the burden of osteoarthritis.Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.The effect of compressive loading magnitude on in situ chondrocyte calcium signaling.Effects of insulin-like growth factor-1 and dexamethasone on cytokine-challenged cartilage: relevance to post-traumatic osteoarthritis.Adipose stem cell microbeads as production sources for chondrogenic growth factors.Impact of cellular microenvironment and mechanical perturbation on calcium signalling in meniscus fibrochondrocytes Hydrogels for the repair of articular cartilage defects Biomechanical influence of cartilage homeostasis in health and disease Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants.Mechanical Loading of Cartilage Explants with Compression and Sliding Motion Modulates Gene Expression of Lubricin and Catabolic Enzymes Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines.Role of proopiomelanocortin-derived peptides and their receptors in the osteoarticular system: from basic to translational research.p21 deficiency is susceptible to osteoarthritis through STAT3 phosphorylation.CD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro model.In vivo intervertebral disc remodeling: kinetics of mRNA expression in response to a single loading event.Regulation of chondrocytic gene expression by biomechanical signals.A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.Cartilage homeostasis in health and rheumatic diseases.Regulation of biomechanical signals by NF-kappaB transcription factors in chondrocytes.Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, tumor necrosis factor-α and interleukin-6, but accentuates degradation above a strain threshold.Novel electrospun scaffolds for the molecular analysis of chondrocytes under dynamic compression.Analysis of ADAMTS4 and MT4-MMP indicates that both are involved in aggrecanolysis in interleukin-1-treated bovine cartilage.

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P2860

Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP

http://www.wikidata.org/entity/Q28244888

description

2004 nî lūn-bûn

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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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Mechanical compression of cart ...... ellular calcium and cyclic AMP

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P1433

Journal of Biological Chemistry

P1476

Mechanical compression of cart ...... ellular calcium and cyclic AMP

@en

P2093

Alan J Grodzinsky

http://www.w3.org/2001/XMLSchema#string

David J Wood

http://www.w3.org/2001/XMLSchema#string

Delphine Dean

http://www.w3.org/2001/XMLSchema#string

Jonathan B Fitzgerald

http://www.w3.org/2001/XMLSchema#string

Ming H Zheng

http://www.w3.org/2001/XMLSchema#string

Moonsoo Jin

http://www.w3.org/2001/XMLSchema#string

P2860

Cluster analysis and display of genome-wide expression patterns

Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta

Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors.

Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage

Biochemical changes in articular cartilage after joint immobilization by casting or external fixation

Biosynthetic response of cartilage explants to dynamic compression

Mechanotransduction via integrins and interleukinâ 4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes

Singular value decomposition for genome-wide expression data processing and modeling

Principal component analysis for clustering gene expression data.

Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in vitro.

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19502-11

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scholarly article

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3798408

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10.1074/JBC.M400437200

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P433

19

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279

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2004-05-07T00:00:00Z

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8694301

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14960571

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