Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.
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Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to ArtemisininsThe redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosisArtemisinin analogues as potent inhibitors of in vitro hepatitis C virus replicationCharacterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line.The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells.Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers.Hispidin induces autophagic and necrotic death in SGC-7901 gastric cancer cells through lysosomal membrane permeabilization by inhibiting tubulin polymerization.Development of artemisinin compounds for cancer treatment.Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cellspH-responsive artemisinin derivatives and lipid nanoparticle formulations inhibit growth of breast cancer cells in vitro and induce down-regulation of HER family members.Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3.Anti-cancer natural products isolated from chinese medicinal herbsAntitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drugDihydroartemisinin increases temozolomide efficacy in glioma cells by inducing autophagy.Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs.Perspective: Opportunities in recalcitrant, rare and neglected tumors.Endoplasmic-reticulum calcium depletion and disease.Anticancer Effect of AntiMalarial Artemisinin Compounds.Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action.Artemisinin and its derivatives in cancer therapy: status of progress, mechanism of action, and future perspectives.Drug target identification in protozoan parasites.Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells.Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.An ultra-high performance chromatographic method for the determination of artemisinin.More insights into the pharmacological effects of artemisinin.
P2860
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P2860
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@en
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@nl
type
label
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@en
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@nl
prefLabel
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@en
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@nl
P2093
P2860
P356
P1476
Artemisinin dimer anticancer a ...... ic reticulum stress induction.
@en
P2093
Ahmed M Galal
Bingnan Han
Desmond Slade
Dianne L Newton
Luke H Stockwin
Mahmoud A ElSohly
Maja A Bumke
Melinda G Hollingshead
Sherry X Yu
Waseem Gul
P2860
P304
P356
10.1002/IJC.24496
P577
2009-09-01T00:00:00Z