Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs - Wikidata - awgldk - TriplyDB

Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs

Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs

http://www.wikidata.org/entity/Q37369753

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Oocyte development, meiosis and aneuploidy The spindle checkpoint and chromosome segregation in meiosis Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes Meiosis and maternal aging: insights from aneuploid oocytes and trisomy births Checkpoint kinase 1 is essential for meiotic cell cycle regulation in mouse oocytes Aurora kinase-A regulates microtubule organizing center (MTOC) localization, chromosome dynamics, and histone-H3 phosphorylation in mouse oocytes Premature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytes Kinetochore microtubule establishment is defective in oocytes from aged mice Age-related increase in aneuploidy and alteration of gene expression in mouse first polar bodies Meiosis I in Xenopus oocytes is not error-prone despite lacking spindle assembly checkpoint.Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.Frequency of aneuploidy related to age in porcine oocytes Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew.Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes.Bioengineering the ovarian follicle microenvironment Applying "gold standards" to in-vitro-derived germ cells.Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies.Animal age, weight and estrus cycle stage impact the quality of in vitro grown follicles Age-dependent susceptibility of chromosome cohesion to premature separase activation in mouse oocytes New insights into the genetic regulation of homologue disjunction in mammalian oocytes.Mouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrest Meiotic origins of maternal age-related aneuploidy.Expression profiles of cohesins, shugoshins and spindle assembly checkpoint genes in rhesus macaque oocytes predict their susceptibility for aneuploidy during embryonic development.Size-specific follicle selection improves mouse oocyte reproductive outcomes.Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes.Isolated primate primordial follicles require a rigid physical environment to survive and grow in vitro Maternal control of early embryogenesis in mammals Age-related aneuploidy through cohesion exhaustion.Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development Lack of response to unaligned chromosomes in mammalian female gametes.RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing.DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age.Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes.Chromosome cohesion decreases in human eggs with advanced maternal age.Hec1-dependent cyclin B2 stabilization regulates the G2-M transition and early prometaphase in mouse oocytes Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity.Why is chromosome segregation error in oocytes increased with maternal aging?

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Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs

http://www.wikidata.org/entity/Q37369753

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Evidence that a defective spin ...... iated aneuploidy in mouse eggs

@en

Evidence that a defective spin ...... ated aneuploidy in mouse eggs.

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type

label

Evidence that a defective spin ...... iated aneuploidy in mouse eggs

@en

Evidence that a defective spin ...... ated aneuploidy in mouse eggs.

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prefLabel

Evidence that a defective spin ...... iated aneuploidy in mouse eggs

@en

Evidence that a defective spin ...... ated aneuploidy in mouse eggs.

@nl

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BIOLREPROD.109.077909

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Biology of Reproduction

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Evidence that a defective spin ...... iated aneuploidy in mouse eggs

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Francesca E Duncan

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Michael A Lampson

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Richard M Schultz

http://www.w3.org/2001/XMLSchema#string

Teresa Chiang

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P2860

How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

Simultaneous analysis of chromosomes and chromosome-associated proteins in mammalian oocytes and embryos

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

To err (meiotically) is human: the genesis of human aneuploidy

RNA Interference as a tool to study the function of MAD2 in mouse oocyte meiotic maturation.

Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I.

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10.1095/BIOLREPROD.109.077909

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