Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development.
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Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalitiesFrom unwitnessed fatality to witnessed rescue: Pharmacologic intervention in sudden unexpected death in epilepsySudden unexpected death in epilepsy: fatal post-ictal respiratory and arousal mechanismsMolecular genetics of mouse serotonin neurons across the lifespan.Mechanisms of sudden unexplained death in epilepsyMolecular underpinnings of ventral surface chemoreceptor function: focus on KCNQ channelsPostnatal changes in tryptophan hydroxylase and serotonin transporter immunoreactivity in multiple brainstem nuclei of the rat: implications for a sensitive periodNeural Control of Breathing and CO2 Homeostasis.Medullary serotonin neurons and their roles in central respiratory chemoreception.Serotonin: a regulator of neuronal morphology and circuitryCentral chemoreceptors: locations and functions.Central serotonin neurons are required for arousal to CO2.From circuits to behaviour: motor networks in vertebratesBradycardia in serotonin-deficient Pet-1-/- mice: influence of respiratory dysfunction and hyperthermia over the first 2 postnatal weeksThe role of medullary serotonin (5-HT) neurons in respiratory control: contributions to eupneic ventilation, CO2 chemoreception, and thermoregulationBrainstem respiratory networks: building blocks and microcircuitsDeletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality.Inducible gene manipulations in brain serotonergic neurons of transgenic rats.Impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1A (Htr1a) receptors.Maternal dietary tryptophan deficiency alters cardiorespiratory control in rat pupsThe serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasisBlockade of neurokinin-1 receptors in the ventral respiratory column does not affect breathing but alters neurochemical release.Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn phox2b heterozygous knock-out mice5HT1A receptors inhibit glutamate inputs to cardiac vagal neurons post-hypoxia/hypercapnia.Brainstem serotonergic deficiency in sudden infant death syndromeDiphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception.Julius H. Comroe, Jr., distinguished lecture: central chemoreception: then ... and now.5-HT2A receptor activation is necessary for CO2-induced arousal.Functional link between the hypocretin and serotonin systems in the neural control of breathing and central chemosensitivityCombined unilateral blockade of cholinergic, peptidergic, and serotonergic receptors in the ventral respiratory column does not affect breathing in awake or sleeping goats.Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null mice.In vitro characterization of noradrenergic modulation of chemosensitive neurons in the retrotrapezoid nucleus.Insomnia Caused by Serotonin Depletion is Due to Hypothermia.Subtle alterations in breathing and heart rate control in the 5-HT1A receptor knockout mouse in early postnatal developmentPostnatal growth defects in mice with constitutive depletion of central serotonin.Serotonergic transcriptional networks and potential importance to mental health.State-dependent interactions between excitatory neuromodulators in the neuronal control of breathing.Partial Raphe Dysfunction in Neurotransmission Is Sufficient to Increase Mortality after Anoxic Exposures in Mice at a Critical Period in Postnatal DevelopmentComputational models and emergent properties of respiratory neural networks.Chronic central serotonin depletion attenuates ventilation and body temperature in young but not adult Tph2 knockout rats.
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Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transgenic mice lacking seroto ...... mortality during development.
@en
Transgenic mice lacking seroto ...... mortality during development.
@nl
type
label
Transgenic mice lacking seroto ...... mortality during development.
@en
Transgenic mice lacking seroto ...... mortality during development.
@nl
prefLabel
Transgenic mice lacking seroto ...... mortality during development.
@en
Transgenic mice lacking seroto ...... mortality during development.
@nl
P2093
P2860
P1476
Transgenic mice lacking seroto ...... h mortality during development
@en
P2093
Jason Aungst
Jeffrey C Smith
Matthew R Hodges
P2860
P304
10341-10349
P356
10.1523/JNEUROSCI.1963-09.2009
P407
P577
2009-08-01T00:00:00Z