Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.

Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.

Item
http://www.wikidata.org/entity/Q37372941
Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.Targeting DNA repair pathways for cancer treatment: what's new?Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity.Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and functionAPE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Pro-apoptotic effects of rHSG on C6 glioma cells.Evidence for base excision repair processing of DNA interstrand crosslinks.Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.Improved efficacy of acylfulvene in colon cancer cells when combined with a nuclear excision repair inhibitor.Molecular inhibitors of DNA repair: searching for the ultimate tumor killing weapon.Receptor-based virtual screening and biological characterization of human apurinic/apyrimidinic endonuclease (Ape1) inhibitors.DNA end-processing enzyme polynucleotide kinase as a potential target in the treatment of cancer.Ferulic acid protects against radiation-induced testicular damage in male rats: impact on SIRT1 and PARP1.Inhibition of CDK4 sensitizes multidrug resistant ovarian cancer cells to paclitaxel by increasing apoptosiss.
P2860

Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.

Item
http://www.wikidata.org/entity/Q37372941
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@en
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@nl
type
label
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@en
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@nl
prefLabel
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@en
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Small-molecule inhibitors of p ...... otherapeutics and irradiation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932