Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.
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Intracellular trafficking of ceramide by ceramide transfer proteinIdentification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptorsSignaling Interactions in the Adrenal CortexMitochondrial function and regulation of macrophage sterol metabolism and inflammatory responsesAlzheimer's disease, oestrogen and mitochondria: an ambiguous relationshipEvolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animalsStem cell therapy for the treatment of Leydig cell dysfunction in primary hypogonadismInfarct-induced steroidogenic acute regulatory protein: a survival role in cardiac fibroblastsMechanisms mediating environmental chemical-induced endocrine disruption in the adrenal glandInteractions between inflammation, sex steroids, and Alzheimer's disease risk factorsTranslocator protein 2 is involved in cholesterol redistribution during erythropoiesisCellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophagesGenomic and neural analysis of the estradiol-synthetic pathway in the zebra finch.Mechanism of testosterone deficiency in the transgenic sickle cell mouse.Transcriptional regulation of translocator protein (Tspo) via a SINE B2-mediated natural antisense transcript in MA-10 Leydig cells.Serotonin transporter (SERT) and translocator protein (TSPO) expression in the obese ob/ob mouseSilencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo.Aging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells.Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormonesAllopregnanolone and neuroinflammation: a focus on multiple sclerosis.The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cellsTSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model.Epigenetic regulation of the expression of genes involved in steroid hormone biosynthesis and action.Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol traffickingEstradiol modulates translocator protein (TSPO) and steroid acute regulatory protein (StAR) via protein kinase A (PKA) signaling in hypothalamic astrocytesCellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.Gonadal transcriptome analysis of male and female olive flounder (Paralichthys olivaceus)Clinical, genetic, and functional characterization of four patients carrying partial loss-of-function mutations in the steroidogenic acute regulatory protein (StAR).Luteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin.Early steps in steroidogenesis: intracellular cholesterol trafficking.Cell cholesterol homeostasis: mediation by active cholesterolPeripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis.Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.Mitochondrial fusion is essential for steroid biosynthesisActivation of the liver X receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy.Cholestenoic Acid is an important elimination product of cholesterol in the retina: comparison of retinal cholesterol metabolism with that in the brain.Mitochondrial protein import and the genesis of steroidogenic mitochondriaNovel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis.Neurosteroids are endogenous neuroprotectants in an ex vivo glaucoma model.
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P2860
Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cholesterol transport in stero ...... mplications in disease states.
@en
Cholesterol transport in stero ...... mplications in disease states.
@nl
type
label
Cholesterol transport in stero ...... mplications in disease states.
@en
Cholesterol transport in stero ...... mplications in disease states.
@nl
prefLabel
Cholesterol transport in stero ...... mplications in disease states.
@en
Cholesterol transport in stero ...... mplications in disease states.
@nl
P2860
P1476
Cholesterol transport in stero ...... implications in disease states
@en
P2093
Malena B Rone
P2860
P304
P356
10.1016/J.BBALIP.2009.03.001
P407
P577
2009-03-12T00:00:00Z