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AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosisEffects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neckThe first 30 years of p53: growing ever more complexMechanisms of drug resistance in colon cancer and its therapeutic strategiesAlterations of the TP53 gene in gastric and esophageal carcinogenesisTP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation.The role of the p53 tumor suppressor in metabolism and diabetesComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterActivation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiformeS6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage responseFATS is a transcriptional target of p53 and associated with antitumor activityA high-enrollment course-based undergraduate research experience improves student conceptions of scientific thinking and ability to interpret dataTargeting MDM2 for Treatment of Adenoid Cystic Carcinoma.Association between TP53 gene Arg72Pro polymorphism and Wilms' tumor risk in a Chinese population.Identification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy.CSF1 is a novel p53 target gene whose protein product functions in a feed-forward manner to suppress apoptosis and enhance p53-mediated growth arrest.The TP53 gene rs1042522 C>G polymorphism and neuroblastoma risk in Chinese children.Validation of dot blot hybridization and denaturing high performance liquid chromatography as reliable methods for TP53 codon 72 genotyping in molecular epidemiologic studiesAssociation of intron and exon polymorphisms of p53 gene in Iranian patients with gastritis.Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an increased risk of esophageal cancer in a Chinese population.The dichotomy of p53 regulation by noncoding RNAs.TP53 Arg72Pro, mortality after cancer, and all-cause mortality in 105,200 individuals.TP53 mutations in human cancers: origins, consequences, and clinical useNo association of the p53 codon 72 polymorphism with malaria in Ghanaian primiparae and Rwandan children.EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesisAtaxia Telangiectasia-Mutated (ATM)Polymorphisms and Risk of Lung Cancer in a Chinese PopulationCharacterization of novel and uncharacterized p53 SNPs in the Chinese population--intron 2 SNP co-segregates with the common codon 72 polymorphismGlucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed.Regulation of MCP-1 chemokine transcription by p53Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.The future of primary intraocular lymphoma (retinal lymphoma).DNA-mediated charge transport in redox sensing and signalingMouse models for the p53 R72P polymorphism mimic human phenotypesProteasomal degradation of p53 by human papillomavirus E6 oncoprotein relies on the structural integrity of p53 core domain.P53 gene polymorphisms and breast cancer risk in Arab women.TP53 Arg72Pro polymorphism and endometrial cancer risk: a meta-analysis.Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls.Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.Genetic variation in microRNA networks: the implications for cancer research.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
p53 polymorphisms: cancer implications.
@en
p53 polymorphisms: cancer implications.
@nl
type
label
p53 polymorphisms: cancer implications.
@en
p53 polymorphisms: cancer implications.
@nl
prefLabel
p53 polymorphisms: cancer implications.
@en
p53 polymorphisms: cancer implications.
@nl
P2860
P356
P1476
p53 polymorphisms: cancer implications.
@en
P2093
Catherine Whibley
Monica Hollstein
P2860
P2888
P304
P356
10.1038/NRC2584
P407
P577
2009-02-01T00:00:00Z