Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
about
Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismHOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.MLL gene rearrangements in infant leukemia vary with age at diagnosis and selected demographic factors: a Children's Oncology Group (COG) study.Polymorphisms in CYP1B1, CYP3A5, GSTT1, and SULT1A1 Are Associated with Early Age Acute LeukemiaModel for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.BRCA1 polymorphisms and breast cancer epidemiology in the Western New York exposures and breast cancer (WEB) studyThe pharmacogenomics of sex hormone metabolism: breast cancer risk in menopausal hormone therapy.Intrauterine growth and childhood leukemia and lymphoma risk.Estradiol induces gene proximity and MLL-MLLT3 fusion in an activation-induced cytidine deaminase-mediated pathway.Localized DNA cleavage secondary to genotoxic exposure adjacent to an Alu inverted repeat.Mixed lineage leukemia histone methylases play critical roles in estrogen-mediated regulation of HOXC13.The distribution of MLL breakpoints correlates with outcome in infant acute leukaemia.
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Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
@en
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
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type
label
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
@en
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
@nl
prefLabel
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
@en
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
@nl
P2093
P2860
P1433
P1476
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells.
@en
P2093
Andrew T Vaughan
Grace A Loredo
Hongan B Le
Sabine Schnyder
Sheetal Singh
P2860
P304
P356
10.1016/J.LEUKRES.2009.01.023
P577
2009-03-05T00:00:00Z