Progranulin deficiency promotes post-ischemic blood-brain barrier disruption
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Therapeutic and diagnostic challenges for frontotemporal dementiaGrowth factors for the treatment of ischemic brain injury (growth factor treatment)Pharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disordersWhite matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort.Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neuronsCellular origin and regulation of D- and L-serine in in vitro and in vivo models of cerebral ischemia.Dichotomous effects of chronic intermittent hypoxia on focal cerebral ischemic injuryDecreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment.Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia.Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection.Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways After Subarachnoid Hemorrhage in Rats.Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells.Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling.Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's DiseaseThe blood-brain barrier after stroke: Structural studies and the role of transcytotic vesicles.Ultrastructural analysis of blood-brain barrier breakdown in the peri-infarct zone in young adult and aged mice.Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia.Therapeutic Strategies to Attenuate Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment for Acute Ischemic StrokeProgranulin and short-term outcome in patients with acute ischaemic stroke.Optimization of Evans blue quantitation in limited rat tissue samples.Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.Alzheimer's disease: A matter of blood-brain barrier dysfunction?The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease.Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease.Progranulin protects against the tissue damage of acute ischaemic stroke.Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke.Progranulin protects against exaggerated axonal injury and astrogliosis following traumatic brain injury.Sulbactam Plays Neuronal Protective Effect Against Brain Ischemia via Upregulating GLT1 in Rats.Frontotemporal dementia: latest evidence and clinical implications.Genetic Deletion of Krüppel-Like Factor 11 Aggravates Ischemic Brain Injury.Regulatory T cells ameliorate tissue plasminogen activator-induced brain haemorrhage after stroke.Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function
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P2860
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption
@en
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption.
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type
label
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption
@en
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption.
@nl
prefLabel
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption
@en
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption.
@nl
P2093
P2860
P1476
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption
@en
P2093
Aihao Ding
Carmen Capone
Diane Lane
Henning Voss
Josef Anrather
Karin Hochrainer
Katherine Jackman
Lidia Garcia-Bonilla
Timo Kahles
P2860
P304
19579-19589
P356
10.1523/JNEUROSCI.4318-13.2013
P407
P577
2013-12-01T00:00:00Z