The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases - Wikidata - awgldk - TriplyDB

The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases

The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases

http://www.wikidata.org/entity/Q37382950

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Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator Membrane trafficking of death receptors: implications on signalling Biochemical and Structural Characterization of the Human TL1A Ectodomain ,Decoy Strategies: The Structure of TL1A:DcR3 Complex On death receptor 3 and its ligands…TNFRSF25 agonistic antibody and galectin-9 combination therapy controls herpes simplex virus-induced immunoinflammatory lesions The role of tumor necrosis factor receptor superfamily members in mammalian brain development, function and homeostasis IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein.TLR8-mediated activation of human monocytes inhibits TL1A expression.Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease The TNF-like protein 1A-death receptor 3 pathway promotes macrophage foam cell formation in vitro.Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.Insights into IBD Pathogenesis.New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding Use of animal models in elucidating disease pathogenesis in IBD.Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.The TNF-family cytokine TL1A inhibits proliferation of human activated B cells Oropharyngeal aspiration of Burkholderia mallei and Burkholderia pseudomallei in BALB/c mice.The adaptor protein TRADD is essential for TNF-like ligand 1A/death receptor 3 signaling.At the bench: understanding group 2 innate lymphoid cells in disease.Progranulin-derived Atsttrin directly binds to TNFRSF25 (DR3) and inhibits TNF-like ligand 1A (TL1A) activity.TNF superfamily in inflammatory disease: translating basic insights.Constitutive TL1A expression under colitogenic conditions modulates the severity and location of gut mucosal inflammation and induces fibrostenosis.Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation.The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation.An essential role for death receptor 3 in experimental autoimmune uveoretinitis.Directed evolution of a soluble human DR3 receptor for the inhibition of TL1A induced cytokine secretion Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia.The role of TRADD in death receptor signaling The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.Recent advances in IBD pathogenesis: genetics and immunobiology.The role of TNF superfamily members in T-cell function and diseases.The role of TL1A and DR3 in autoimmune and inflammatory diseases.TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation.Natural killer T cells and the regulation of asthma.

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The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases

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J.IMMUNI.2008.04.021

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The TNF-family receptor DR3 is ...... mediated inflammatory diseases

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Andrea Keane-Myers

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Dragana Jankovic

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Erin Kahle

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Ethan M Shevach

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Françoise Meylan

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Krishika Acharya

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Marcus Hodges

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Michelle Kinder

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Richard M Siegel

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Todd S Davidson

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P2860

TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing

A gene atlas of the mouse and human protein-encoding transcriptomes

TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

TNF/TNFR family members in costimulation of T cell responses

Death receptor 3 (DR3) gene duplication in a chromosome region 1p36.3: gene duplication is more prevalent in rheumatoid arthritis

OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity

Costimulatory molecule OX40L is critical for both Th1 and Th2 responses in allergic inflammation

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