LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
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Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activationChemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processesLithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cellsMammalian target of rapamycin (mTOR): conducting the cellular signaling symphonyUnexploited Antineoplastic Effects of Commercially Available Anti-Diabetic DrugsNatural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic InfectionAMPK as a potential anticancer target - friend or foe?The PI3K/Akt/mTOR pathway in ovarian cancer: therapeutic opportunities and challengesRegulation of cardiac autophagy by insulin-like growth factor 1The role of autophagy in Drosophila metamorphosisRegulation of Ketone Body Metabolism and the Role of PPARαSignalling scaffolds and local organization of cellular behaviourExcessive Leucine-mTORC1-Signalling of Cow Milk-Based Infant Formula: The Missing Link to Understand Early Childhood ObesityRapamycin reverses paraquat-induced acute lung injury in a rat model through inhibition of NFκB activationHypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK PathwayIn Vitro Anti-Echinococcal and Metabolic Effects of Metformin Involve Activation of AMP-Activated Protein Kinase in Larval Stages of Echinococcus granulosusG9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell CarcinomaMetformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived XenograftsLeucine signaling in the pathogenesis of type 2 diabetes and obesityRegulation of the mTOR complex 1 pathway by nutrients, growth factors, and stressAblation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.Lycorine Induces Apoptosis of A549 Cells via AMPK-Mammalian Target of Rapamycin (mTOR)-S6K Signaling Pathway.Sestrin 1 ameliorates cardiac hypertrophy via autophagy activation.AMPK activation--protean potential for boosting healthspan.The alleviative effects of metformin for lipopolysaccharide-induced acute lung injury rat model and its underlying mechanism.20S-Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1-AMP-activated protein kinase activation.Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer.Autophagy: cellular and molecular mechanisms.TOR signaling never gets old: aging, longevity and TORC1 activity.Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway.AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis.AMP-activated kinase restricts Rift Valley fever virus infection by inhibiting fatty acid synthesis.Aging biology: a new frontier for drug discovery.Enhancement of recombinant human EPO production and glycosylation in serum-free suspension culture of CHO cells through expression and supplementation of 30Kc19.Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications.Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function.KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene.
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P2860
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@en
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@nl
type
label
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@en
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@nl
prefLabel
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@en
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@nl
P2860
P1433
P1476
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
@en
P2093
P2860
P356
10.1111/J.1748-1716.2009.01972.X
P577
2009-02-19T00:00:00Z