The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells.
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Genes and Pathways Involved in Adult Onset Disorders Featuring Muscle Mitochondrial DNA InstabilityAtad3 function is essential for early post-implantation development in the mousePolg2 is essential for mammalian embryogenesis and is required for mtDNA maintenanceWhole cell formaldehyde cross-linking simplifies purification of mitochondrial nucleoids and associated proteins involved in mitochondrial gene expressionActin and myosin contribute to mammalian mitochondrial DNA maintenance.The road to rack and ruin: selecting deleterious mitochondrial DNA variantsNuclear respiratory factor 2 induces the expression of many but not all human proteins acting in mitochondrial DNA transcription and replicationA mechanistic view of human mitochondrial DNA polymerase gamma: providing insight into drug toxicity and mitochondrial diseaseMitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome.Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels.DNA damage and base excision repair in mitochondria and their role in aging.RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial EncephalomyopathyIdentification and characterization of a novel HIV-1 nucleotide-competing reverse transcriptase inhibitor series.REXO2 is an oligoribonuclease active in human mitochondria.Biochemical analysis of human POLG2 variants associated with mitochondrial disease.Evolution of the metazoan mitochondrial replicase.Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndromeIdentification of a Mitochondrial DNA Polymerase Affecting Cardiotoxicity of Sunitinib Using a Genome-Wide Screening on S. pombe Deletion Library.Animal models of mitochondrial DNA transactions in disease and ageingMitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.Reduced mtDNA copy number increases the sensitivity of tumor cells to chemotherapeutic drugs.Mitochondrial disease in childhood: mtDNA encoded.The mitochondrial nucleoid: integrating mitochondrial DNA into cellular homeostasisThe association of the mitochondrial DNA OriB variant (16184-16193 polycytosine tract) with type 2 diabetes in Europid populationsAnimal Mitochondrial DNA Replication.Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria.PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations.Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin.Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitorsPOLG2 deficiency causes adult-onset syndromic sensory neuropathy, ataxia and parkinsonism.Live imaging reveals the dynamics and regulation of mitochondrial nucleoids during the cell cycle in Fucci2-HeLa cells.Differential regulation of full-length genome and a single-stranded 7S DNA along the cell cycle in human mitochondria.Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet β-cells of diabetic Goto Kakizaki rats.Nuclear genes involved in mitochondrial diseases caused by instability of mitochondrial DNA.Suppression of mitochondrial transcription initiation complexes changes the balance of replication intermediates of mitochondrial DNA and reduces 7S DNA in cultured human cells.Droplet digital PCR shows the D-Loop to be an error prone locus for mitochondrial DNA copy number determination
P2860
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P2860
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The accessory subunit of mitoc ...... eoids in human cultured cells.
@en
The accessory subunit of mitoc ...... eoids in human cultured cells.
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type
label
The accessory subunit of mitoc ...... eoids in human cultured cells.
@en
The accessory subunit of mitoc ...... eoids in human cultured cells.
@nl
prefLabel
The accessory subunit of mitoc ...... eoids in human cultured cells.
@en
The accessory subunit of mitoc ...... eoids in human cultured cells.
@nl
P2093
P2860
P356
P1476
The accessory subunit of mitoc ...... eoids in human cultured cells.
@en
P2093
A R Fersht
H Sembongi
J D Boyd-Kirkup
J N Spelbrink
L J Bailey
P Martinsson
P2860
P304
P356
10.1093/NAR/GKP614
P407
P577
2009-07-22T00:00:00Z