Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
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Identification of STAT5A and STAT5B target genes in human T cellsGenomic views of STAT function in CD4+ T helper cell differentiationIL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiationThe involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitisEarly signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsetsATP-dependent chromatin remodeling in T cellsLack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosisSTAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cellsDifferentiation of effector CD4 T cell populations (*)ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experimentsVariable structure motifs for transcription factor binding sites.T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii.New insights into the regulation of T cells by gamma(c) family cytokinesImmune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders: an evolving web of heritable autoimmune diseases.The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.Dysregulated cytokine expression by CD4+ T cells from post-septic mice modulates both Th1 and Th2-mediated granulomatous lung inflammationSTEME: efficient EM to find motifs in large data setsBCL6 controls Th9 cell development by repressing Il9 transcription.IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme.Complex interactions of transcription factors in mediating cytokine biology in T cells.Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modulesGenome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cellsTranscriptional and epigenetic regulation of T-helper lineage specification.Targeting the JAK-STAT pathway in lymphoma: a focus on pacritinib.Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.Differential regulation of IL-4Ralpha expression by antigen versus cytokine stimulation characterizes Th2 progression in vivoRequirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia.Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements.SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses.Application of ChIP-Seq and related techniques to the study of immune function.FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells.Post-operative infection and sepsis in humans is associated with deficient gene expression of γc cytokines and their apoptosis mediatorsInterleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site VModulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages.C/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion.Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses.T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.
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P2860
Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 September 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Priming for T helper type 2 di ...... eceptor alpha-chain expression
@en
Priming for T helper type 2 di ...... ceptor alpha-chain expression.
@nl
type
label
Priming for T helper type 2 di ...... eceptor alpha-chain expression
@en
Priming for T helper type 2 di ...... ceptor alpha-chain expression.
@nl
prefLabel
Priming for T helper type 2 di ...... eceptor alpha-chain expression
@en
Priming for T helper type 2 di ...... ceptor alpha-chain expression.
@nl
P2093
P2860
P356
P1433
P1476
Priming for T helper type 2 di ...... eceptor alpha-chain expression
@en
P2093
Dustin E Schones
Jangsuk Oh
Kairong Cui
Tae-Young Roh
Warren J Leonard
Yongzhi Cui
P2860
P304
P356
10.1038/NI.1656
P407
P577
2008-09-28T00:00:00Z