Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
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Roles for retrotransposon insertions in human diseaseThe structure and function of NKAIN2-a candidate tumor suppressorBreaching the nuclear envelope in development and diseaseReplication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast.Chromothripsis from DNA damage in micronuclei.The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancersHistory and evolution of cytogeneticsThe cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elementsA fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.A new light on DNA replication from the inactive X chromosomeTowards accurate characterization of clonal heterogeneity based on structural variationSpatial and temporal diversity in genomic instability processes defines lung cancer evolution.Error-Prone Repair of DNA Double-Strand Breaks.Functional chromatin features are associated with structural mutations in cancerShatterProof: operational detection and quantification of chromothripsis.Chromosome-breakage genomic instability and chromothripsis in breast cancerTracking the origins and drivers of subclonal metastatic expansion in prostate cancer.Catastrophic chromosomal restructuring during genome elimination in plants.Programmed Genome Rearrangements in the Ciliate Oxytricha.Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine.Genome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome.Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics.Mechanisms for Complex Chromosomal Insertions.Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome.FANCA safeguards interphase and mitosis during hematopoiesis in vivo.Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencingChromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans.Turning the headlights on novel cancer biomarkers: Inspection of mechanics underlying intratumor heterogeneityA high-throughput in vivo micronucleus assay for genome instability screening in miceThe tandem duplicator phenotype as a distinct genomic configuration in cancerCOSMOS: accurate detection of somatic structural variations through asymmetric comparison between tumor and normal samplesSpatiotemporal control of estrogen-responsive transcription in ERα-positive breast cancer cells.Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypesLow miR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma.Nuclear Noncoding RNAs and Genome Stability.Linking genomic reorganization to tumor initiation via the giant cell cycleIdentification of complex genomic rearrangements in cancers using CouGaRSomatic structural variation and cancer.Chromosomal Rearrangements in Cancer: Detection and potential causal mechanisms.Chromothripsis in cancer cells: An update.
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Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
@en
Chromothripsis and beyond: rap ...... ex chromosomal rearrangements.
@nl
type
label
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
@en
Chromothripsis and beyond: rap ...... ex chromosomal rearrangements.
@nl
prefLabel
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
@en
Chromothripsis and beyond: rap ...... ex chromosomal rearrangements.
@nl
P2860
P356
P1433
P1476
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
@en
P2093
Cheng-Zhong Zhang
David Pellman
P2860
P304
P356
10.1101/GAD.229559.113
P577
2013-12-01T00:00:00Z