about
Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidationAPOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT studyEffects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor bindingAPOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy menGenetic variants in novel pathways influence blood pressure and cardiovascular disease riskBlood pressure loci identified with a gene-centric arrayIntegrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease riskGene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChipTriglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studiesAPOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levelsAssociation between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant dataPopulation genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) ConsortiumCholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular riskGene Ontology Consortium: going forwardMendelian randomization of blood lipids for coronary heart disease.Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes lociEffect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovascular diseases.A common single-nucleotide variant in T is strongly associated with chordoma.Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.APOE, CETP and LPL genes show strong association with lipid levels in Greek childrenSeparating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variationGene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical TrialThe impact of focused Gene Ontology curation of specific mammalian systemsApplication of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene.A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels.Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arraysNovel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levelsCommon variation in the lipoprotein lipase gene: effects on plasma lipids and risk of atherosclerosis.Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with HeightA systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart diseaseGene:environment interaction in lipid metabolism and effect on coronary heart disease risk.HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study.
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P50
description
South African geneticist
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geneticista sul-africana
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geneticus uit Zuid-Afrika
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genetista hegoafrikarra
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genetista sud-africana
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genetista sudafricana
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genetista sudafricana
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géineolaí as an Afraic Theas
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généticienne sud-africaine
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xenetista sudafricana
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Philippa J Talmud
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Philippa J Talmud
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Philippa J Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa J Talmud
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Philippa J Talmud
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Philippa J Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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P J Talmud
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Philippa J. Talmud
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Philippa J. Talmud
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Philippa J. Talmud
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Philippa J. Talmud
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Philippa J Talmud
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Philippa J Talmud
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Philippa J Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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Philippa Talmud
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0000-0002-5560-1933