A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell.
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PML nuclear bodiesThe non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phasePlzf regulates germline progenitor self-renewal by opposing mTORC1Redox regulation in cancer: a double-edged sword with therapeutic potential.PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal.Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.Glucocorticoid receptors in the retina, Müller glia and the formation of Müller glia-derived progenitors.Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells.Akt-signal integration is involved in the differentiation of embryonal carcinoma cellsDistinct germline progenitor subsets defined through Tsc2-mTORC1 signaling.Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.Maintenance therapy in ovarian cancer: Molecular basis and therapeutic approach.Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn miceMicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.Adult Stem Cells and Diseases of Aging.Targeting leukemic stem cells by breaking their dormancyOxidative stress and therapeutic opportunities: focus on the Ewing's sarcoma family of tumors.Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies.Adenosine-to-inosine RNA editing meets cancer.Role of the promyelocytic leukaemia protein in cell death regulation.Emerging role of microRNAs in cancer and cancer stem cells.Kinase-inhibitor-insensitive cancer stem cells in chronic myeloid leukemia.Melanoma epigenetics: novel mechanisms, markers, and medicines.Phosphatase of regenerating liver in hematopoietic stem cells and hematological malignancies.Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells.Gamma interferon-dependent transcriptional memory via relocalization of a gene locus to PML nuclear bodies.Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway.p-mTOR expression is associated with better prognosis in luminal breast carcinoma.Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells.BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP.
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A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A novel signaling network as a ...... nd the cancer-initiating cell.
@en
A novel signaling network as a ...... nd the cancer-initiating cell.
@nl
type
label
A novel signaling network as a ...... nd the cancer-initiating cell.
@en
A novel signaling network as a ...... nd the cancer-initiating cell.
@nl
prefLabel
A novel signaling network as a ...... nd the cancer-initiating cell.
@en
A novel signaling network as a ...... nd the cancer-initiating cell.
@nl
P2860
P1476
A novel signaling network as a ...... nd the cancer-initiating cell.
@en
P2093
Keisuke Ito
Rosa Bernardi
P2860
P356
10.1016/J.GDE.2009.01.004
P577
2009-02-11T00:00:00Z