Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4. - Wikidata - awgldk - TriplyDB

Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.

Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.

http://www.wikidata.org/entity/Q37396904

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Targeting hypoxic response for cancer therapy Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis Stromal Fibroblast in Age-Related Cancer: Role in Tumorigenesis and Potential as Novel Therapeutic Target Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer Sustained proliferation in cancer: Mechanisms and novel therapeutic targets Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts.Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase.Caveolin-1 is a modulator of fibroblast activation and a potential biomarker for gastric cancer.Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts Thyroid Cancer Metabolism: A Review Monocarboxylate transporters in the brain and in cancer.JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines Pivotal role of pervasive neoplastic and stromal cells reprogramming in circulating tumor cells dissemination and metastatic colonization.Remodeling of extracellular matrix of the lamina propria in the uninvolved human rectal mucosa 10 and 20 cm away from the malignant tumor.Critical transitions in a game theoretic model of tumour metabolism The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy.Transformation by different oncogenes relies on specific metabolic adaptations.Multicompartment metabolism in papillary thyroid cancer Eugenol inhibits oxidative phosphorylation and fatty acid oxidation via downregulation of c-Myc/PGC-1β/ERRα signaling pathway in MCF10A-ras cells Cancer metabolism: new validated targets for drug discovery.Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance.Metformin Effects on Metabolic Coupling and Tumor Growth in Oral Cavity Squamous Cell Carcinoma Coinjection Xenografts.Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.Oxidative Phosphorylation: A Target for Novel Therapeutic Strategies Against Ovarian Cancer An overview of MCT1 and MCT4 in GBM: small molecule transporters with large implications

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Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.

http://www.wikidata.org/entity/Q37396904

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 08 July 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

@en

Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

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type

label

Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

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Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

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prefLabel

Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

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Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

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Oncogenes and inflammation rew ...... and NFκB target stromal MCT4.

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Alessandro Bombonati

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David Cognetti

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Edmund Pribitkin

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Madalina Tuluc

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Richard G Pestell

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Ying-Hui Ko

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Zhao Lin

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P2860

The Hallmarks of Cancer

Hallmarks of Cancer: The Next Generation

Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment

Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers

Stromal cell expression of caveolin-1 predicts outcome in breast cancer

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2580-2597

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scholarly article

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10.4161/CC.25510

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16

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12

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Ubaldo E Martinez-Outschoorn

Michael P. Lisanti

Federica Sotgia

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2013-07-08T00:00:00Z

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249965490

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23860378

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