about
Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice.Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease.Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis.The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity.The janus head of T cell aging - autoimmunity and immunodeficiency.Estradiol targets T cell signaling pathways in human systemic lupus.Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.Signals and Receptors.PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans.Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Antigen receptor signaling in the rheumatic diseases
@en
Antigen receptor signaling in the rheumatic diseases.
@nl
type
label
Antigen receptor signaling in the rheumatic diseases
@en
Antigen receptor signaling in the rheumatic diseases.
@nl
prefLabel
Antigen receptor signaling in the rheumatic diseases
@en
Antigen receptor signaling in the rheumatic diseases.
@nl
P2860
P921
P356
P1476
Antigen receptor signaling in the rheumatic diseases
@en
P2860
P2888
P356
10.1186/AR2528
P577
2009-01-30T00:00:00Z
P5875
P6179
1047146488