SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond - Wikidata - awgldk - TriplyDB

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

http://www.wikidata.org/entity/Q28298645

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Function, regulation and pathological roles of the Gab/DOS docking proteins Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development Cooperative interactions at the SLP-76 complex are critical for actin polymerization SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells T cell activation Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapse Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP)SLP-65 phosphorylation dynamics reveals a functional basis for signal integration by receptor-proximal adaptor proteins Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner.Mechanism and function of Vav1 localisation in TCR signalling.SH2-dependent autophosphorylation within the Tec family kinase Itk.T cell antigen receptor signaling and immunological synapse stability require myosin IIA Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells.T-cell artificial focal triggering tools: linking surface interactions with cell response.Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in node-positive bladder cancer.Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strain Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45 SLP76 integrates into the B-cell receptor signaling cascade in chronic lymphocytic leukemia cells and is associated with an aggressive disease course T-cell signaling regulated by the Tec family kinase, Itk.Spatial association of signaling proteins and F-actin effects on cluster assembly analyzed via photoactivation localization microscopy in T cells Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cells Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.Pregnancy induces transcriptional activation of the peripheral innate immune system and increases oxidative DNA damage among healthy third trimester pregnant women.Adapters in the organization of mast cell signaling.Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K.BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activation.Itk: the rheostat of the T cell response.The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

http://www.wikidata.org/entity/Q28298645

description

2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2006 թվականի հունվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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type

label

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

@en

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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prefLabel

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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Nature Reviews Immunology

P1476

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

@en

P2093

Farhad Abtahian

http://www.w3.org/2001/XMLSchema#string

Gary A Koretzky

http://www.w3.org/2001/XMLSchema#string

Michael A Silverman

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P2860

Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes

An essential role for BLNK in human B cell development

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

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67-78

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scholarly article

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4300291

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10.1038/NRI1750

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1

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6

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1001692527

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16493428

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