Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein.
about
Sensitivity of cancer cells to truncated diphtheria toxin.Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutantsMalignant melanoma and melanocortin 1 receptor.Cardiac allograft survival in mice treated with IL-2-PE40.A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxinMelanotropin receptors demonstrated in situ in human melanomaSequential effects of interleukin 2-diphtheria toxin fusion protein on T-cell activationActivity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxinMechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process.A circularly permuted recombinant interleukin 4 toxin with increased activity.Analysis of the diphtheria tox promoter by site-directed mutagenesis.Cloning and expression in Escherichia coli of three fragments of diphtheria toxin truncated within fragment B.High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coliInterleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion proteinEpidermal growth factor receptor binding is affected by structural determinants in the toxin domain of transforming growth factor-alpha-Pseudomonas exotoxin fusion proteins.Protein engineering of DAB-IL-2 fusion toxins to increase biologic potency.Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignanciesImmunotoxins in the therapy of leukemias and lymphomas.Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.pH-triggered conformational switching along the membrane insertion pathway of the diphtheria toxin T-domainPolymeric drug-carriers containing doxorubicin and melanocyte-stimulating hormone: in vitro and in vivo evaluation against murine melanoma.On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.Stimulation of the receptor for melanocyte-stimulating hormone by retinoic acid.Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence.A quantitative comparison of cytosolic delivery via different protein uptake systems.Cellular Entry of the Diphtheria Toxin Does Not Require the Formation of the Open-Channel State by Its Translocation Domain.Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.Cytotoxicity of a recombinant diphtheria toxin-granulocyte colony-stimulating factor fusion protein on human leukemic blast cells.Cell receptor specific targeted toxins: genetic construction and characterization of an interleukin 2 diphtheria toxin-related fusion protein.
P2860
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P2860
Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Genetic construction, expressi ...... lating hormone fusion protein.
@en
Genetic construction, expressi ...... lating hormone fusion protein.
@nl
type
label
Genetic construction, expressi ...... lating hormone fusion protein.
@en
Genetic construction, expressi ...... lating hormone fusion protein.
@nl
prefLabel
Genetic construction, expressi ...... lating hormone fusion protein.
@en
Genetic construction, expressi ...... lating hormone fusion protein.
@nl
P2093
P2860
P356
P1476
Genetic construction, expressi ...... lating hormone fusion protein.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.21.8258
P407
P577
1986-11-01T00:00:00Z