A circularly permuted recombinant interleukin 4 toxin with increased activity.
about
In vivo formation of allosteric aspartate transcarbamoylase containing circularly permuted catalytic polypeptide chains: implications for protein folding and assemblyToxin-based targeted therapy for malignant brain tumorsDevelopment of a recombinant interleukin-4-Pseudomonas exotoxin for therapy of glioblastoma.Immunotoxins.SV40 Pseudovirion gene delivery of a toxin to treat human adenocarcinomas in mice.Clinical development of experimental therapies for malignant glioma.Hodgkin lymphoma therapy with interleukin-4 receptor-directed cytotoxin in an infiltrating animal modelCircular permutation within the coenzyme binding domain of the tetrameric glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus.Interleukin-4 receptor expression on AIDS-associated Kaposi's sarcoma cells and their targeting by a chimeric protein comprised of circularly permuted interleukin-4 and Pseudomonas exotoxin.Convection-enhanced and local delivery of targeted cytotoxins in the treatment of malignant gliomas.Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy.In vivo assembly of aspartate transcarbamoylase from fragmented and circularly permuted catalytic polypeptide chains.IL-4 receptors on human medulloblastoma tumours serve as a sensitive target for a circular permuted IL-4-Pseudomonas exotoxin fusion proteinRandom circular permutation of genes and expressed polypeptide chains: application of the method to the catalytic chains of aspartate transcarbamoylase.A novel reduced immunogenicity bispecific targeted toxin simultaneously recognizing human epidermal growth factor and interleukin-4 receptors in a mouse model of metastatic breast carcinoma.Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activityRecombinant toxins in haematologic malignancies and solid tumours.
P2860
Q21045405-44EE2EF0-A749-464B-8570-D160B38917E8Q27006226-850E6760-501E-41B2-B1E3-CB27B0F32CF3Q33657635-49E7566D-E3BE-44F9-8406-FEEC89A4B287Q34181903-B7BB4216-7AE9-4ACA-A3A4-D71170294B02Q34695978-CB82A049-A6AF-4A91-AE27-EC81DA957F52Q34782295-F03AAFA9-5793-4E70-9531-A2DF0EA7630BQ35847498-FA2BEFB1-EEE1-48AA-A463-8FD1F80B58E9Q36279175-AD57E3A0-8BF0-4B00-B26E-DB30422349B0Q36437751-6C5A98AA-71C5-425C-8EEE-2D08C564C545Q36478643-D3E2B75D-75B2-400B-973D-1EA3BF98CA91Q36478656-B81371F5-0E6D-4620-88A1-76327AA9E109Q36640559-45AA2EBA-1AF0-42B8-B623-75B6E3E088B0Q36643654-8F069F81-D993-456D-95CE-D2709043768BQ37260556-794FBB6E-666F-46DB-A632-C4A27AA05A62Q37373289-365E917B-5BB4-4460-949A-7FE327D131DFQ37400550-959BA3BB-DA4A-436D-86DB-00F3C4B39AE2Q53668245-8F816E2F-619E-4190-B902-AC7DE86A87D4
P2860
A circularly permuted recombinant interleukin 4 toxin with increased activity.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@ast
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@en
type
label
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@ast
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@en
prefLabel
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@ast
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@en
P2093
P2860
P356
P1476
A circularly permuted recombinant interleukin 4 toxin with increased activity.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.15.6889
P407
P577
1994-07-01T00:00:00Z